Aim of the study A vast majority of human malignancies are associated with ageing, and age
is a strong predictor of cancer risk. Recently, DNA methylation-based marker of ageing …

Age is a key risk factor for breast cancer and epigenetic alterations may contribute to age-
related increases in breast cancer risk, though the relation of age-related methylation in …

The incidence of cancer, adjusted for secular trends, is directly related to age, and advanced
chronologic age is one of the most significant risk factors for cancer. Organismal aging is …

Background The underlying biological mechanisms through which epidemiologically
defined breast cancer risk factors contribute to disease risk remain poorly understood …

Cancer is well established as an age‐associated disease, and there is substantial overlap in
the molecular, cellular and physiological changes observed with both ageing and the …

Background Age is one of the most important risk factors for developing breast cancer.
However, age-related changes in normal breast tissue that potentially lead to breast cancer …

Background Previous studies have developed models predicting methylation age from DNA
methylation in blood and other tissues (epigenetic clock) and suggested the difference …

Background DNA methylation is a potential biomarker for early detection of breast cancer.
However, robust evidence of a prospective relationship between DNA methylation patterns …

Background Limited evidence suggests that female breast tissue ages faster than other parts
of the body according to an epigenetic biomarker of aging known as the “epigenetic clock.” …

Background Age is one of the strongest predictors of cancer, chronic disease, and mortality,
but biological responses to aging differ among people. Epigenetic DNA modifications have …