[PDF][PDF] The BRAIN initiative cell census consortium: lessons learned toward generating a comprehensive brain cell atlas

JR Ecker, DH Geschwind, AR Kriegstein, J Ngai… - Neuron, 2017 - cell.com
A comprehensive characterization of neuronal cell types, their distributions, and patterns of
connectivity is critical for understanding the properties of neural circuits and how they …

[HTML][HTML] A cell atlas for the mouse brain

C Erö, MO Gewaltig, D Keller… - Frontiers in …, 2018 - frontiersin.org
Despite vast numbers of studies of stained cells in the mouse brain, no current brain atlas
provides region-by-region neuron counts. In fact, neuron numbers are only available for …

[PDF][PDF] Molecular architecture of the mouse nervous system

A Zeisel, H Hochgerner, P Lönnerberg, A Johnsson… - Cell, 2018 - cell.com
The mammalian nervous system executes complex behaviors controlled by specialized,
precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a …

[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain

Z Yao, CTJ van Velthoven, M Kunst, M Zhang… - Nature, 2023 - nature.com
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …

[PDF][PDF] BRAIN 2.0: Transforming neuroscience

J Ngai - Cell, 2022 - cell.com
Summary The NIH BRAIN Initiative is entering a new phase. Three large new projects—a
comprehensive human brain cell atlas, a whole mammalian brain microconnectivity map …

[PDF][PDF] Molecular diversity and specializations among the cells of the adult mouse brain

A Saunders, EZ Macosko, A Wysoker, M Goldman… - Cell, 2018 - cell.com
The mammalian brain is composed of diverse, specialized cell populations. To
systematically ascertain and learn from these cellular specializations, we used Drop-seq to …

From cell types to an integrated understanding of brain evolution: the case of the cerebral cortex

MA Tosches - Annual Review of Cell and Developmental …, 2021 - annualreviews.org
With the discovery of the incredible diversity of neurons, Cajal and coworkers laid the
foundation of modern neuroscience. Neuron types are not only structural units of nervous …

Molecularly defined and spatially resolved cell atlas of the whole mouse brain

M Zhang, X Pan, W Jung, AR Halpern, SW Eichhorn… - Nature, 2023 - nature.com
In mammalian brains, millions to billions of cells form complex interaction networks to enable
a wide range of functions. The enormous diversity and intricate organization of cells have …

A guide to the BRAIN Initiative Cell Census Network data ecosystem

M Hawrylycz, ME Martone, GA Ascoli, JG Bjaalie… - PLoS …, 2023 - journals.plos.org
Characterizing cellular diversity at different levels of biological organization and across data
modalities is a prerequisite to understanding the function of cell types in the brain …

An interactive framework for whole-brain maps at cellular resolution

D Fürth, T Vaissière, O Tzortzi, Y Xuan, A Märtin… - Nature …, 2018 - nature.com
To deconstruct the architecture and function of brain circuits, it is necessary to generate
maps of neuronal connectivity and activity on a whole-brain scale. New methods now …