The vagus nerve in the neuro-immune axis: implications in the pathology of the gastrointestinal tract

B Bonaz, V Sinniger, S Pellissier - Frontiers in immunology, 2017 - frontiersin.org
The vagus nerve (VN) is the longest nerve of the organism and a major component of the
parasympathetic nervous system which constitutes the autonomic nervous system (ANS) …

Anti‐inflammatory effects of vagal nerve stimulation with a special attention to intestinal barrier dysfunction

B Bonaz - Neurogastroenterology & Motility, 2022 - Wiley Online Library
The vagus nerve (VN), the longest nerve of the organism innervating the gastrointestinal
tract, is a mixed nerve with anti‐inflammatory properties through its afferents, activating the …

Therapeutic potential of vagus nerve stimulation for inflammatory bowel diseases

B Bonaz, V Sinniger, S Pellissier - Frontiers in neuroscience, 2021 - frontiersin.org
The vagus nerve is a mixed nerve, comprising 80% afferent fibers and 20% efferent fibers. It
allows a bidirectional communication between the central nervous system and the digestive …

[HTML][HTML] The vagus nerve at the interface of the microbiota-gut-brain axis

B Bonaz, T Bazin, S Pellissier - Frontiers in neuroscience, 2018 - frontiersin.org
The microbiota, the gut, and the brain communicate through the microbiota-gut-brain axis in
a bidirectional way that involves the autonomic nervous system. The vagus nerve (VN), the …

Vagus nerve stimulation: from epilepsy to the cholinergic anti‐inflammatory pathway

B Bonaz, C Picq, V Sinniger, JF Mayol… - …, 2013 - Wiley Online Library
Background The brain and the gut communicate bidirectionally through the autonomic
nervous system (ANS). The vagus nerve (VN), a major component of the ANS, plays a key …

The vagal innervation of the gut and immune homeostasis

G Matteoli, GE Boeckxstaens - Gut, 2013 - gut.bmj.com
The central nervous system interacts dynamically with the immune system to modulate
inflammation through humoral and neural pathways. Recently, in animal models of sepsis …

Anti‐inflammatory properties of the vagus nerve: potential therapeutic implications of vagus nerve stimulation

B Bonaz, V Sinniger, S Pellissier - The Journal of physiology, 2016 - Wiley Online Library
Brain and viscera interplay within the autonomic nervous system where the vagus nerve
(VN), containing approximately 80% afferent and 20% efferent fibres, plays multiple key …

The vagus nerve as a modulator of intestinal inflammation

EP Van Der Zanden, GE Boeckxstaens… - …, 2009 - Wiley Online Library
The cholinergic nervous system attenuates the production of pro‐inflammatory cytokines
and inhibits inflammatory processes. Hence, in animal models of intestinal inflammation …

Vagus nerve stimulation at the interface of brain–gut interactions

B Bonaz, V Sinniger… - Cold Spring …, 2019 - perspectivesinmedicine.cshlp.org
The vagus nerve, a key component of the cross-communication between the gut and the
brain, is a major element of homeostasis sensing the “milieu intérieur” and boosting the …

The vagus nerve in appetite regulation, mood, and intestinal inflammation

KN Browning, S Verheijden, GE Boeckxstaens - Gastroenterology, 2017 - Elsevier
Although the gastrointestinal tract contains intrinsic neural plexuses that allow a significant
degree of independent control over gastrointestinal functions, the central nervous system …