Transcriptional regulatory networks (TRNs) have been studied intensely for> 25 y. Yet, even
for the Escherichia coli TRN—probably the best characterized TRN—several questions …

A transcriptional regulatory network (TRN) constitutes the collection of regulatory rules that
link environmental cues to the transcription state of a cell's genome. We recently proposed a …

Recent studies of genome-wide transcriptional regulatory network (TRN) revealed several
intriguing structural and dynamic features of gene expression at a system level …

Predicting the quantitative regulatory function of transcription factors (TFs) based on factors
such as binding sequence, binding location, and promoter type is not possible. The …

Bacteria regulate gene expression to adapt to changing environments through
transcriptional regulatory networks (TRNs). Although extensively studied, no TRN is fully …

Taking advantage of available functional data associated with 115 transcription and 7 sigma
factors, we have performed a structural analysis of the regulatory network of Escherichia coli …

Transcriptional regulation enables cells to respond to environmental changes. Of the
estimated 304 candidate transcription factors (TFs) in Escherichia coli K-12 MG1655, 185 …

Underlying cellular responses is a transcriptional regulatory network (TRN) that modulates
gene expression. A useful description of the TRN would decompose the transcriptome into …

Transcription is an essential step in gene expression and its understanding has been one of
the major interests in molecular and cellular biology. By precisely tuning gene expression …

Despite almost 40 years of molecular genetics research in Escherichia coli a major fraction
of its Transcription Start Sites (TSSs) are still unknown, limiting therefore our understanding …