Neuroimmunology and neuroepigenetics in the establishment of sex differences in the brain

MM McCarthy, BM Nugent, KM Lenz - Nature Reviews Neuroscience, 2017 - nature.com
The study of sex differences in the brain is a topic of neuroscientific study that has broad
reaching implications for culture, society and biomedical science. Recent research in rodent …

A new view of sexual differentiation of mammalian brain

MM McCarthy - Journal of Comparative Physiology A, 2020 - Springer
Establishment of enduring sex differences in brain and behavior occurs during pre-or
perinatal development, depending on species. For over 50 years the focus has been on …

It is not all hormones: alternative explanations for sexual differentiation of the brain

W Davies, LS Wilkinson - Brain research, 2006 - Elsevier
Males and females of many species differ with regard to neurodevelopment, ongoing brain
function and behavior. For many years, it was assumed that these differences primarily …

Surprising origins of sex differences in the brain

MM McCarthy, LA Pickett, JW VanRyzin… - Hormones and behavior, 2015 - Elsevier
This article is part of a Special Issue “SBN 2014”. Discerning the biologic origins of
neuroanatomical sex differences has been of interest since they were first reported in the …

Brain sex differences and hormone influences: a moving experience?

S Tobet, JG Knoll, C Hartshorn… - Journal of …, 2009 - Wiley Online Library
Sex differences in the nervous system come in many forms. Although a majority of sexually
dimorphic characteristics in the brain have been described in older animals, mechanisms …

The complex relationships between sex and the brain

D Joel, A Garcia-Falgueras, D Swaab - The Neuroscientist, 2020 - journals.sagepub.com
In the past decennia, our understanding of the sexual differentiation of the mammalian brain
has dramatically changed. The simple model according to which testosterone masculinizes …

Sex differences in the developing brain as a source of inherent risk

MM McCarthy - Dialogues in clinical neuroscience, 2016 - Taylor & Francis
Brain development diverges in males and females in response to androgen production by
the fetal testis. This sexual differentiation of the brain occurs during a sensitive window and …

Minireview: sex differences in adult and developing brains: compensation, compensation, compensation

GJ De Vries - Endocrinology, 2004 - academic.oup.com
Despite decades of research, we do not know the functional significance of most sex
differences in the brain. We are heavily invested in the idea that sex differences in brain …

[HTML][HTML] Incorporating sex as a biological variable in neuropsychiatric research: where are we now and where should we be?

D Joel, MM Mccarthy - Neuropsychopharmacology, 2017 - nature.com
Understanding the multiplicity of ways in which sex can alter the brain is essential to crafting
policies and treatments that are beneficial for all human beings. This is particularly true for …

Minireview: sex chromosomes and brain sexual differentiation

AP Arnold, J Xu, W Grisham, X Chen, YH Kim… - …, 2004 - academic.oup.com
The brains of males and females differ, not only in regions specialized for reproduction, but
also in other regions (controlling cognition, for example) where sex differences are not …