Pre-implantation embryo development is an intricate and precisely regulated process
orchestrated by maternally inherited proteins and newly synthesized proteins following …

Mammalian pre-implantation development is a complex process involving dramatic changes
in the transcriptional architecture,,,. We report here a comprehensive analysis of …

Genetic studies on the mammalian preimplantation embryo are providing a wealth of
information regarding gene expression. However, changes in the transcriptome do not …

Human preimplantation development involves extensive remodeling of RNA expression and
splicing. However, its transcriptome has been compiled using short-read sequencing data …

The preimplantation development of the mammalian embryo encompasses a series of
critical events: the transition from oocyte to embryo, the first cell divisions, the establishment …

Background During mammalian pre-implantation embryonic development dramatic and
orchestrated changes occur in gene transcription. The identification of the complete changes …

Early mouse embryos have an atypical translational machinery that consists of cytoplasmic
lattices and is poorly competent for translation. Hence, the impact of transcriptomic changes …

Studies using low-resolution methods to assess gene expression during preimplantation
mouse development indicate that changes in gene expression either precede or occur …

During mouse preimplantation embryo development, totipotent blastomeres generate the
first three cell lineages of the embryo: trophectoderm, epiblast and primitive endoderm. In …

The preimplantation mouse embryo is a simple self-contained system, making it an excellent
model to discover how mammalian cells function in real time and in vivo. Work over the last …