Introduction Renal sodium (Na+) retention and extracellular fluid volume expansion are
hallmarks of nephrotic syndrome, which occurs even in the absence of activation of …

Sodium and fluid retention is a hallmark and a therapeutic challenge of the nephrotic
syndrome (NS). Studies support the “overfill” theory of NS with pathophysiological proteolytic …

Objective: Diabetic nephropathy is associated with aberrant glomerular filtration of serine
proteases. The study was designed to test the hypothesis that the epithelial sodium channel …

Sodium retention is a major clinical feature of nephrotic syndrome. The mechanisms
responsible for sodium retention in this setting have been a subject of debate for years …

Albuminuria in kidney transplant recipients (KTRs) is associated with hypertension and
aberrant glomerular filtration of serine proteases that may proteolytically activate the …

In conditions with albuminuria, plasminogen is aberrantly filtered across the glomerular
barrier and activated along the tubular system to plasmin. In the collecting duct, plasmin …

Double-blind, randomized controlled studies of longer than 1 week in duration comparing
the antiproteinuric potential of long-acting dihydropyridine calcium channel blockers with …

We investigated the effects of 3 days treatment with acetazolamide 250 mg three times daily
on kidney function in 8 Type 1 (insulin-dependent) diabetic patients with nephropathy, and …

The nephrotic syndrome is a frequent clinical condition characterized by fluid and salt
retention. Although several theories have been put forward to explain the saltretaining …

Albuterol and insulin for treatment of hyperkalemia in hemodialysis patients. We evaluated
in maintenance hemodialysis patients the potassium lowering effects of intravenous insulin …