The sequence of nucleosomal DNA modulates sliding by the Chd1 chromatin remodeler
J Winger, GD Bowman - Journal of molecular biology, 2017 - Elsevier
Chromatin remodelers are ATP-dependent enzymes that are critical for reorganizing and
repositioning nucleosomes in concert with many basic cellular processes. For the …
repositioning nucleosomes in concert with many basic cellular processes. For the …
Identification of residues in chromodomain helicase DNA-binding protein 1 (Chd1) required for coupling ATP hydrolysis to nucleosome sliding
Chromatin remodelers are ATP-dependent machines responsible for directionally shifting
nucleosomes along DNA. We are interested in defining which elements of the …
nucleosomes along DNA. We are interested in defining which elements of the …
Interdomain communication of the Chd1 chromatin remodeler across the DNA gyres of the nucleosome
Chromatin remodelers use a helicase-like ATPase motor to reposition and reorganize
nucleosomes along genomic DNA. Yet, how the ATPase motor communicates with other …
nucleosomes along genomic DNA. Yet, how the ATPase motor communicates with other …
Bi-directional nucleosome sliding by the Chd1 chromatin remodeler integrates intrinsic sequence-dependent and ATP-dependent nucleosome positioning
Chromatin remodelers use a helicase-type ATPase motor to shift DNA around the histone
core. Although not directly reading out the DNA sequence, some chromatin remodelers …
core. Although not directly reading out the DNA sequence, some chromatin remodelers …
Nucleosome recognition and DNA distortion by the Chd1 remodeler in a nucleotide-free state
Chromatin remodelers are ATP-dependent enzymes that reorganize nucleosomes within all
eukaryotic genomes. Here we report a complex of the Chd1 remodeler bound to a …
eukaryotic genomes. Here we report a complex of the Chd1 remodeler bound to a …
The Chd1 chromatin remodeler shifts nucleosomal DNA bidirectionally as a monomer
Chromatin remodelers catalyze dynamic packaging of the genome by carrying out
nucleosome assembly/disassembly, histone exchange, and nucleosome repositioning …
nucleosome assembly/disassembly, histone exchange, and nucleosome repositioning …
The tumor suppressor chromodomain helicase DNA-binding protein 5 (CHD5) remodels nucleosomes by unwrapping
J Quan, T Yusufzai - Journal of Biological Chemistry, 2014 - ASBMB
Although mutations or deletions of chromodomain helicase DNA-binding protein 5 (CHD5)
have been linked to cancer and implicate CHD5 in tumor suppression, the ATP-dependent …
have been linked to cancer and implicate CHD5 in tumor suppression, the ATP-dependent …
The chromodomains of the Chd1 chromatin remodeler regulate DNA access to the ATPase motor
G Hauk, JN McKnight, IM Nodelman, GD Bowman - Molecular cell, 2010 - cell.com
Chromatin remodelers are ATP-driven machines that assemble, slide, and remove
nucleosomes from DNA, but how the ATPase motors of remodelers are regulated is poorly …
nucleosomes from DNA, but how the ATPase motors of remodelers are regulated is poorly …
The ATPase motor of the Chd1 chromatin remodeler stimulates DNA unwrapping from the nucleosome
Chromatin remodelers are ATP-dependent motors that reorganize DNA packaging by
disrupting canonical histone–DNA contacts within the nucleosome. Here, we show that the …
disrupting canonical histone–DNA contacts within the nucleosome. Here, we show that the …
Extranucleosomal DNA binding directs nucleosome sliding by Chd1
JN McKnight, KR Jenkins, IM Nodelman… - … and cellular biology, 2011 - Taylor & Francis
Chd1-and ISWI-type chromatin remodelers can sense extranucleosomal DNA and
preferentially shift nucleosomes toward longer stretches of available DNA. The DNA-binding …
preferentially shift nucleosomes toward longer stretches of available DNA. The DNA-binding …