Abstract Autism Spectrum Disorder (ASD) and Tourette syndrome (TS) are poorly
understood neurodevelopment disorders with strong male bias, high heritability and …

Tourette syndrome (TS) is a neurodevelopmental disorder characterised by motor and vocal
tics and strong association with autistic deficits, obsessive–compulsive disorder (OCD) and …

Tourette syndrome (TS) is a highly heritable neuropsychiatric disorder characterised by
motor and vocal tics. Despite decades of research, the aetiology of TS has remained elusive …

Autism spectrum disorder (ASD) is appropriately named due to the broad variability or
clinical heterogeneity, which in turn is linked to genetic heterogeneity. Such clinical …

Tourette syndrome (TS) is a model neuropsychiatric disorder thought to arise from abnormal
development and/or maintenance of cortico-striato-thalamo-cortical circuits. TS is highly …

Tuberous sclerosis complex (TSC) is a rare monogenic disorder co-diagnosed with high
rates of autism and is caused by loss of function mutations in the TSC1 or TSC2 genes. A …

Over the past 3 decades, the prevalence of autism spectrum disorder (ASD) has increased
globally from 20 to 28 million cases making ASD the fastest-growing developmental …

Gilles de la Tourette syndrome (GTS) is a neuropsychiatric disorder characterized by
multiple motor and vocal tics. GTS is a complex disorder, with environmental factors and …

Background Autism spectrum disorder (ASD) is reported in 30 to 60% of patients with
tuberous sclerosis complex (TSC) but shared genetic mechanisms that exist between TSC …

α-Catenins (CTNNAs) are essential for the regulation of cell–cell and cell–matrix interactions
in tissues. All human CTNNA genes contain antisense oriented leucine rich repeat …