The results of this work stem from the collaborative efforts of the labs from PD Dr. Philipp
Korber, Prof. B. Franklin Pugh, PhD., Prof. Craig L. Peterson, PhD., and Prof. Dr. Karl-Peter …

The eukaryotic genome is packaged into chromatin, which renders the DNA inaccessible to
DNA-templated cellular processes. These include DNA replication, repair, recombination …

Knowing the explicit locations of nucleosomes in a genome is a pre-requisite for
understanding the regulation of genes. Predominantly at regulatory active promoter sites …

Recent genome-wide mapping of nucleosome positions revealed that well-positioned
nucleosomes are pervasive across eukaryotic genomes, especially in important regulatory …

Chromatin remodelers regulate genes by organizing nucleosomes around promoters, but
their individual contributions are obfuscated by the complex in vivo milieu of factor …

The fundamental molecular determinants by which ATP-dependent chromatin remodelers
organize nucleosomes across eukaryotic genomes remain largely elusive. Here, chromatin …

Nucleosome positioning is crucial for the genome's function. Though the role of DNA
sequence in positioning nucleosomes is well understood, a detailed mechanistic …

Arrays of regularly spaced nucleosomes dominate chromatin and are often phased by
alignment to reference sites like active promoters. How the distances between nucleosomes …

The fundamental molecular determinants by which ATP-dependent chromatin remodelers
organize nucleosomes across eukaryotic genomes remain largely elusive. Here, chromatin …

Regulation of chromatin structure is essential for controlling access of DNA to factors that
require association with specific DNA sequences. Here we describe the development and …