Gcn5‐dependent histone H3 acetylation and gene activity is required for the asexual development and virulence of Beauveria bassiana

Q Cai, JJ Wang, B Fu, SH Ying… - Environmental …, 2018 - Wiley Online Library
Gcn5 is a core histone acetyltransferase that catalyzes histone H3 acetylation on N‐terminal
lysine residues in yeasts and was reported to catalyze H3K9/K14 acetylation required for …

Mapping dynamic histone modification patterns during arsenic-induced malignant transformation of human bladder cells

Y Ge, J Zhu, X Wang, N Zheng, C Tu, J Qu… - Toxicology and applied …, 2018 - Elsevier
Arsenic is a known potent risk factor for bladder cancer. Increasing evidence suggests that
epigenetic alterations, eg, DNA methylation and histones posttranslational modifications …

Modified polynucleotides for the production of cosmetic proteins and peptides

S Bancel, EYC Huang - US Patent 9,878,056, 2018 - Google Patents
2014-12-18 Assigned to MODERNA THERAPEUTICS, INC. reassignment MODERNA
THERAPEUTICS, INC. CORRECTIVE ASSIGNMENT TO CORRECT THE RECEIVING …

Modified nucleosides, nucleotides, and nucleic acids, and uses thereof

JP Schrum, S Siddiqi, K Ejebe - US Patent 10,064,959, 2018 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
45893552&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Metabolism as a signal generator across trans-omic networks at distinct time scales

K Yugi, S Kuroda - Current Opinion in Systems Biology, 2018 - Elsevier
Metabolism not only involves outcomes of signal transduction, gene expression, and
chromatin/DNA modification but also serves as a signal generator across omic layers …

Downregulation of decidual SP1 and P300 is associated with severe preeclampsia

Y Zhang, J Yang, S Lv, DQ Zhao… - Journal of …, 2018 - jme.bioscientifica.com
Preeclampsia (PE) is a pregnancy-induced disorder characterized by hypertension and
proteinuria after 20 weeks of gestation, affecting 5–7% of pregnancies worldwide. So far, the …

Histones and heart failure in diabetes

VG Yerra, A Advani - Cellular and Molecular Life Sciences, 2018 - Springer
Although heart failure is now accepted as being a major long-term complication of diabetes,
many of the recent advances in our understanding of the pathobiology of diabetes …

LPS promotes HBO1 stability via USP25 to modulate inflammatory gene transcription in THP-1 cells

C Long, Y Lai, J Li, J Huang, C Zou - Biochimica et Biophysica Acta (BBA) …, 2018 - Elsevier
The histone acetyltransferase HBO1 (Histone acetyltransferase binding to origin recognition
complex 1, Myst2/Kat7) participates in a range of life processes including DNA replication …

Enhancer function regulated by combinations of transcription factors and cofactors

T Nakagawa, M Yoneda, M Higashi, Y Ohkuma… - Genes to …, 2018 - Wiley Online Library
Regulation of the expression of diverse genes is essential for making possible the
complexity of higher organisms, and the temporal and spatial regulation of gene expression …

Histone acetyltransferases (HATs) in Chinese cabbage: insights from histone H3 acetylation and expression profiling of HATs in response to abiotic stresses

SH Eom, TK Hyun - Journal of the American Society for …, 2018 - journals.ashs.org
Histone acetyltransferase (HAT) is known as an epigenetic enzyme that acetylates specific
lysine residues on the histone tail to promote chromatin dynamics and gene expression. In …