Engineered nucleic acids and methods of use thereof
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Scriptaid improves the reprogramming of donor cells and enhances canine-porcine interspecies embryo development
JG No, TY Hur, M Zhao, S Lee, MK Choi, YS Nam… - Reproductive …, 2018 - Elsevier
Histone methylation, histone acetylation, and DNA methylation are the important factors for
somatic cell nuclear transfer (SCNT). Histone deacetylase inhibitors (HDACi) and DNA …
somatic cell nuclear transfer (SCNT). Histone deacetylase inhibitors (HDACi) and DNA …
The lysine acetylome of the nematocidal bacterium Bacillus nematocida and impact of nematode on the acetylome
XL Sun, YH Yang, L Zhu, FY Liu, JP Xu, XW Huang… - Journal of …, 2018 - Elsevier
Abstract Bacillus nematocida B16 (B16) is a pathogenic bacterium that is nematotoxic to
plant-parasitic nematodes. In this study, we performed a quantitative lysine acetylome …
plant-parasitic nematodes. In this study, we performed a quantitative lysine acetylome …
Recent trends on the role of epigenomics, metabolomics and noncoding RNAs in rationalizing mood stabilizing treatment
Mood stabilizers are the cornerstone in treatment of mood disorders, but their use is
characterized by high interindividual variability. This feature has stimulated intensive …
characterized by high interindividual variability. This feature has stimulated intensive …
Delivery and formulation of engineered nucleic acids
A De Fougerolles, SM Elbashir - US Patent 9,950,068, 2018 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
46147671&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
46147671&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Under explored epigenetic modulators: role in glioma chemotherapy
YH Chen, W Zeng, Z Wen, Q Cheng… - European Journal of …, 2018 - Elsevier
Patients with somatic mutations of epigenetic regulators are characterized by aberrant
chromatin modification patterns. Recent mechanistic studies pairing chemical tool …
chromatin modification patterns. Recent mechanistic studies pairing chemical tool …
Designing epigenome editors: considerations of biochemical and locus specificities
D Sen, AJ Keung - Epigenome Editing: Methods and Protocols, 2018 - Springer
The advent of locus-specific protein recruitment technologies has enabled a new class of
studies in chromatin biology. Epigenome editors enable biochemical modifications of …
studies in chromatin biology. Epigenome editors enable biochemical modifications of …
Histone modifications and transcription in plants
YL Chua, JC Gray - Annual Plant Reviews online, 2018 - Wiley Online Library
The N-terminal tails of histones H3 and H4 are modified post-translationally by acetylation
and methylation. Acetylation of histones is reversible and dynamic, whereas histone …
and methylation. Acetylation of histones is reversible and dynamic, whereas histone …
Untersuchung der epigenetischen Funktionen von Lysin‐Acetyltransferasen mit Methoden der chemischen Biologie
Abstract Die Seitenkettenacetylierung von Lysinresten in Histonen und Nicht‐Histon‐
Proteinen durch Katalyse mit Lysin‐Acetyltransferasen (KATs) ist eine häufige …
Proteinen durch Katalyse mit Lysin‐Acetyltransferasen (KATs) ist eine häufige …
[PDF][PDF] In silico design and optimisation of Phytoalexin resveratrol polyphenolic analogs as inhibitors of histone acetyltransferase for the Management of Tumor Growth
R Hammett, C Shoemake - Med Chem, 2018 - researchgate.net
Cancer cells are known to be more susceptible to deoxyribonucleic acid (DNA) damage
than normal ones due to their genetic instability. The post-translation modification of …
than normal ones due to their genetic instability. The post-translation modification of …