Objective Treatment of maternal depression with psychotherapy has been shown to confer
indirect benefits to school-age offspring with psychiatric disorders. The current study sought …

Background In the last years, several studies focused on the role of Gene-Environment
interactions (GxE) in influencing psychopathological outcomes among maltreated children …

Childhood adversities frequently precede adulthood depression and anxiety. Yet, how they
impact needed treatment duration, type or focus in these common disorders, is unclear. For …

Objective Around 30–50% of patients with depression and anxiety disorders fail to respond
to standard psychological therapy. Given that cortisol affects cognition, patients with altered …

Background Inflammation may play an important role in depression and its treatment. A
previous study found that increased C-reactive protein (CRP), a marker of systemic …

Background Types of maltreatment often co-occur and it is unclear how maltreatment
patterns impact on comorbidity in depressed patients. Methods We analysed associations of …

Research on factors associated with good mental health following child maltreatment is
often based on unrepresentative adult samples. To address these limitations, the current …

Objectives Many studies examined predictors of depressive relapse/recurrence but no
simple tool based on well-established risk factors is available that estimates the risk within …

Childhood trauma has been proposed to increase vulnerability to develop psychopathology
in part through an altered cortisol stress response. Research in rats has suggested that this …

Childhood trauma (CT), including sexual, emotional, physical abuse, and physical and
emotional neglect, is one of the most consistent predictors of major depressive disorder …