Understanding the genetic underpinning of early human development is of great interest not
only for basic developmental and stem cell biology but also for regenerative medicine …

The phylogenomics and comparative functional genomics of avian species were
investigated in the Bird 10,000 Genomes (B10K) project because of the important …

There exist some patients who face recurrent total fertilization failure during assisted
reproduction treatment, but the pathological mechanism underlying is elusive. Here, by …

In recent years, exciting progress was made to improve the embryo outcome after ovarian
stimulation in domestic animals. The practice of follicle-stimulating hormone (FSH) …

Sexually transmitted infections with Chlamydia trachomatis and/or Neisseria gonorrhoeae
and rates of pelvic inflammatory disease (PID) in women continue to rise, with reinfection …

Survival and cell death signals are crucial for mammalian embryo preimplantation
development. However, the knowledge on the molecular mechanisms underlying their …

Non-coding RNAs (ncRNAs) have significant regulatory functions on the regulation of gene
expression of various life activities after transcription, even though they do not encode …

Background ETCHbox genes are eutherian-specific homeobox genes expressed during
preimplantation development at a time when the first cell lineage decisions are being made …

De novo mutations (DNMs) have been shown to be a major cause of severe early-onset
genetic disorders such as autism spectrum disorder and intellectual disability. Over one …

STUDY QUESTION What is the difference between the gene expression profiles of single
human germinal vesicle (GV) oocytes from women of different ages? SUMMARY ANSWER …