Excessive daytime sleepiness (EDS) is one of the earliest and most common non-motor
symptoms of PD, substantially impacting on patient's quality of life. Using the Parkinson's …

Background. The current classification of tremor types in Parkinson disease (PD) is
potentially confusing, particularly for mixed tremor, and there is no label for pure resting …

Selegiline hydrochloride (SL), is an anti-Parkinson's agent, has low-oral bioavailability due
to its high first pass metabolism and scarce oral absorption. In the present study, SL …

End-of-dose motor fluctuations are regarded as one of the core troublesome symptoms by
patients with Parkinson's disease (PD). Treatment of levodopa (l-dopa)-induced motor …

When Parkinson's disease (PD) patients are asked about the quality of their sleep, their
answers are dominated by difficulties associated with impaired mobility in bed, medically …

Background and purpose Pain is highly prevalent in Parkinson's disease (PD), impacting
patients' ability, mood and quality of life. Detecting the presence of pain in its multiple …

Background and purpose Pain is a frequent and debilitating non-motor symptom of
Idiopathic Parkinson's Disease (IPD). The present study investigated the prevalence of pain …

Abstract Background Patients with Parkinson disease (PD) and their partners report
deterioration in their sexual life. Sexual dysfunction (SD), an important and often ignored …

Abstract Background People with PD (PWP) have an increased risk of becoming inactive.
Wearable sensors can provide insights into daily physical activity and walking patterns …

Parkinson's disease (PD) is a progressive and incurable neurodegenerative disorder. In this
study, we utilized SHSY5Y cells an in vitro PD model to study the biological function of …