Follicle capacitation: a meta-analysis to investigate the transcriptome dynamics following follicle-stimulating hormone decline in bovine granulosa cells

DA Landry, MA Sirard - Biology of Reproduction, 2018 - academic.oup.com
In recent years, exciting progress was made to improve the embryo outcome after ovarian
stimulation in domestic animals. The practice of follicle-stimulating hormone (FSH) …

Changes in granulosa cells' gene expression associated with increased oocyte competence in bovine

AL Nivet, C Vigneault, P Blondin, MA Sirard - Reproduction, 2013 - rep.bioscientifica.com
One of the challenges in mammalian reproduction is to understand the basic physiology of
oocyte quality. It is believed that the follicle status is linked to developmental competence of …

Transcriptomic signature of the follicular somatic compartment surrounding an oocyte with high developmental competence

S Sugimura, N Kobayashi, H Okae, T Yamanouchi… - Scientific reports, 2017 - nature.com
During antral folliculogenesis, developmental competence of prospective oocytes is
regulated in large part by the follicular somatic component to prepare the oocyte for the final …

Transcriptome analysis of granulosa cells after conventional vs long FSH-induced superstimulation in cattle

FCF Dias, MIR Khan, MA Sirard, GP Adams, J Singh - BMC genomics, 2018 - Springer
Background Prolongation of superstimulatory treatment appears to be associated with a
greater superovulatory response and with greater oocyte maturation in cattle. A genome …

Transcriptome meta-analysis of three follicular compartments and its correlation with ovarian follicle maturity and oocyte developmental competence in cows

DR Khan, DA Landry, É Fournier… - Physiological …, 2016 - journals.physiology.org
Oocyte developmental competence in superstimulated cows is dependent in part on the
duration of the FSH coasting. FSH coasting refers to superstimulation with FSH (2 days of …

Follicular hyperstimulation dysgenesis: new explanation for adverse effects of excessive FSH in ovarian stimulation

ZL Clark, ML Ruebel, PZ Schall, KR Karl… - …, 2022 - academic.oup.com
High follicle-stimulating hormone (FSH) doses during ovarian stimulation protocols for
assisted reproductive technologies (ART) are detrimental to ovulatory follicle function and …

Comparative analysis of granulosa cell gene expression in association with oocyte competence in FSH-stimulated Holstein cows

DA Landry, C Fortin, AM Bellefleur… - Reproduction …, 2017 - CSIRO Publishing
Ovarian stimulation with exogenous FSH followed by FSH withdrawal or 'coasting'is an
effective means of increasing the number of oocytes obtainable for the in vitro production of …

Influence of luteinizing hormone support on granulosa cells transcriptome in cattle

AL Nivet, C Vigneault, P Blondin… - Animal Science …, 2018 - Wiley Online Library
In cows, the use of follicle‐stimulating hormone (FSH) to stimulate follicular growth followed
by a short period of FSH withdrawal has been shown to be beneficial for oocyte …

Expression of atresia biomarkers in granulosa cells after ovarian stimulation in heifers

DA Landry, L Rossi-Perazza, S Lafontaine… - …, 2018 - rep.bioscientifica.com
The use of younger gamete donors in dairy cattle genetic selection programs significantly
accelerates genetic gains by decreasing the interval between generations. Ovarian …

The global effect of follicle-stimulating hormone and tumour necrosis factor α on gene expression in cultured bovine ovarian granulosa cells

C Glister, N Hatzirodos, K Hummitzsch, PG Knight… - BMC genomics, 2014 - Springer
Background Oocytes mature in ovarian follicles surrounded by granulosa cells. During
follicle growth, granulosa cells replicate and secrete hormones, particularly steroids close to …