There is a continued predisposition of concurrent use of drugs and botanical products.
Consumers often self-administer botanical products without informing their health care …

There is a continued predisposition of concurrent use of drugs and botanical products. A
general lack of knowledge of the interaction potential together with an under-reporting of …

Supported by a usage history that predates written records and the perception that “natural”
ensures safety, herbal products have increasingly been incorporated into Western health …

The potential for various natural products to perturb the metabolism and disposition of
medications has been recognized for decades. There are numerous in vitro and in vivo …

Although the potential of an interaction between concurrently administered botanical and
pharmaceutical products is not unexpected, this topic has received increased attention and …

The popularity of botanical products in the United States is reflected in a survey on
complementary and alternative medicine that showed that American consumers had spent …

People mistakenly think that all herbs are safe, because of the fact that they are natural, and
the use of herbal medication is growing. Aspects of the efficacy, safety, and quality of herbal …

Although there are inherent and recognized limitations of in vitro screening methodologies
to assess conventional drug-drug interactions (DDIs) per industry guidelines and those …

Exposure to botanicals in dietary supplements is increasing across many geographies; with
increased expectations from consumers, regulators, and industry stewards centered on …

In Part 2 of this review, a critical examination of the pertinent scientific literature is
undertaken in order to assess the interaction risk that popular dietary supplements may pose …