Gene-environment interaction and psychiatric disorders: Review and future directions

E Assary, JP Vincent, R Keers, M Pluess - Seminars in cell & …, 2018 - Elsevier
Empirical studies suggest that psychiatric disorders result from a complex interplay between
genetic and environmental factors. Most evidence for such gene-environment interaction …

Gene× environment interactions: from molecular mechanisms to behavior

T Halldorsdottir, EB Binder - Annual Review of Psychology, 2017 - annualreviews.org
Gene-by-environment interactions (G× Es) can provide important biological insights into
psychiatric disorders and may consequently have direct clinical implications. In this review …

Gene–environment interactions in common mental disorders: an update and strategy for a genome-wide search

R Uher - Social psychiatry and psychiatric epidemiology, 2014 - Springer
A decade of research has demonstrated the explanatory potential of interplay between
genetic variants and environmental factors in the development of common mental disorders …

Gene-environment interactions in psychiatry: recent evidence and clinical implications

RJ Musci, JL Augustinavicius, H Volk - Current psychiatry reports, 2019 - Springer
Abstract Purpose of Review We identify the recent evidence for gene-by-environment
interaction studies in relation to psychiatric disorders. We focus on the key genotypic data as …

Mind the gap: Why many geneticists and psychological scientists have discrepant views about gene–environment interaction (G× E) research.

LE Duncan, AR Pollastri, JW Smoller - American Psychologist, 2014 - psycnet.apa.org
As our field seeks to elucidate the biopsychosocial etiologies of mental health disorders,
many traditional psychological and social science researchers have added, or plan to add …

Gene–environment interactions in psychiatry: joining forces with neuroscience

A Caspi, TE Moffitt - Nature Reviews Neuroscience, 2006 - nature.com
Gene–environment interaction research in psychiatry is new, and is a natural ally of
neuroscience. Mental disorders have known environmental causes, but there is …

Gene–environment interplay and psychopathology: Multiple varieties but real effects

M Rutter, TE Moffitt, A Caspi - Journal of child Psychology and …, 2006 - Wiley Online Library
Gene–environment interplay is a general term that covers several divergent concepts with
different meanings and different implications. In this review, we evaluate research evidence …

[HTML][HTML] Gene-environment interaction in evolutionary perspective: differential susceptibility to environmental influences

J Belsky, S Hartman - World Psychiatry, 2014 - ncbi.nlm.nih.gov
By tradition, psychiatrists have been concerned with the nature, origins, sequelae and
treatment of mental disorders. When it comes to etiology and the role of genetics, psychiatric …

Candidate gene–environment interaction research: Reflections and recommendations

DM Dick, A Agrawal, MC Keller… - Perspectives on …, 2015 - journals.sagepub.com
Studying how genetic predispositions come together with environmental factors to contribute
to complex behavioral outcomes has great potential for advancing the understanding of the …

Gene–environment interactions in genome‐wide association studies: current approaches and new directions

SJ Winham, JM Biernacka - Journal of Child Psychology and …, 2013 - Wiley Online Library
Background Complex psychiatric traits have long been thought to be the result of a
combination of genetic and environmental factors, and gene–environment interactions are …