Background One third of patients with major depressive disorder (MDD) fail to respond to
currently available antidepressant medications. Inflammation may contribute to treatment …

Despite the evidence of an association between depression and increased inflammatory
markers, still little is known in relation to the most severe cases of the disorder ie, those who …

Background Treatment-resistant depression (TRD) contributes substantially to the burden of
mood disorders and is undoubtedly an important subpopulation in whom there are clear …

Inflammation may correlate with a specific subgroup of depression and differential
antidepressant response, but no trial has studied changes of many inflammatory markers …

The depressive state has been characterised as one of elevated inflammation, which holds
promise for better understanding treatment-resistance in affective disorders as well as for …

Background A substantial percentage of depressed patients do not respond satisfactorily to
conventional antidepressant treatment. This treatment resistant depression (TRD) may be …

Rationale Evidence suggests that depression is cross-sectionally and longitudinally
associated with activation of inflammatory response system. A few studies, however, have …

Inflammation has been involved in the pathophysiology and treatment response of major
depressive disorder (MDD). Plasma cytokine profiles of 171 treatment-naive MDD patients …

Objective: Major depressive disorder has been linked with inflammatory processes, but it is
unclear whether individual differences in levels of inflammatory biomarkers could help …

Scarce evidence suggests that inflammatory and metabolic dysregulation predicts poor
response to antidepressants, which could result in worse depression outcome. This study …