Single-cell non-coding RNA in embryonic development

Q Fu, CJ Liu, ZS Zhai, X Zhang, T Qin… - Single Cell …, 2018 - Springer
Non-coding RNAs (ncRNAs) have significant regulatory functions on the regulation of gene
expression of various life activities after transcription, even though they do not encode …

The functions of microRNAs and long non-coding RNAs in embryonic and induced pluripotent stem cells

W Jia, W Chen, J Kang - Genomics, proteomics & bioinformatics, 2013 - academic.oup.com
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) hold immense
promise for regenerative medicine due to their abilities to self-renew and to differentiate into …

[HTML][HTML] Non-coding RNAs: multi-tasking molecules in the cell

AQ Gomes, S Nolasco, H Soares - International journal of molecular …, 2013 - mdpi.com
In the last years it has become increasingly clear that the mammalian transcriptome is highly
complex and includes a large number of small non-coding RNAs (sncRNAs) and long …

Long noncoding RNA mediated regulation in human embryogenesis, pluripotency, and reproduction

L Liu, F Fang - Stem Cells International, 2022 - Wiley Online Library
Long noncoding RNAs (lncRNAs), a class of noncoding RNAs with more than 200 bp in
length, are produced by pervasive transcription in mammalian genomes and regulate gene …

A PCR-based method for detection and quantification of small RNAs

S Ro, C Park, J Jin, KM Sanders, W Yan - Biochemical and biophysical …, 2006 - Elsevier
Recent cloning efforts have identified hundreds of thousands of small RNAs including micro
RNAs (miRNAs), Piwi-interacting RNAs (piRNAs), and small nucleolar RNAs (snoRNAs) …

Single cell transcriptomics of noncoding RNAs and their cell‐specificity

KAB Gawronski, J Kim - Wiley Interdisciplinary Reviews: RNA, 2017 - Wiley Online Library
Recent developments of single cell transcriptome profiling methods have led to the
realization that many seemingly homogeneous cells have surprising levels of expression …

Long non-coding RNAs in human early embryonic development and their potential in ART

J Bouckenheimer, S Assou, S Riquier… - Human …, 2017 - academic.oup.com
BACKGROUND Human long non-coding RNAs (lncRNAs) are an emerging category of
transcripts with increasingly documented functional roles during development. LncRNAs …

Long noncoding RNAs in human stemness and differentiation

FM Azad, IL Polignano, V Proserpio, S Oliviero - Trends in Cell Biology, 2021 - cell.com
There is increasing evidence that long noncoding RNAs (lncRNAs) are among the main
regulatory factors of stem cell maintenance and differentiation. They act through various …

Small non-coding RNAs in the human placenta: regulatory roles and clinical utility

N Telkar, GL Stewart, ME Pewarchuk, DE Cohn… - Frontiers in …, 2022 - frontiersin.org
The placenta is a vital organ formed during pregnancy, and being the interface between the
mother and fetus, it is paramount that placental functioning is strictly controlled. Gene …

Large noncoding RNAs are promising regulators in embryonic stem cells

YP Li, Y Wang - Journal of Genetics and Genomics, 2015 - Elsevier
Embryonic stem cells (ESCs) hold great promises for treating and studying numerous
devastating diseases. The molecular basis of their potential is not completely understood …