Age predictors based on DNA methylation levels at a small set of CpG sites, DNAm clocks,
have been developed for humans and extended to several other species. Three currently …

Aging as an irretrievable occurrence throughout the entire life is characterized by a
progressive decline in physiological functionality and enhanced disease vulnerability …

Aging is often perceived as a degenerative process resulting from random accrual of cellular
damage over time. Despite this, age can be accurately estimated by epigenetic clocks based …

The DNA methylation levels of certain CpG sites are thought to reflect the pace of human
aging. Here, we developed a robust predictor of mouse biological age based on 90 CpG …

Human DNA-methylation data have been used to develop highly accurate biomarkers of
aging (" epigenetic clocks"). Recent studies demonstrate that similar epigenetic clocks for …

Epigenetic clocks for mice were generated based on deep-sequencing analysis of the
methylome. Here, we demonstrate that site-specific analysis of DNA methylation levels by …

The number of age predictors based on DNA methylation (DNAm) profile is rising due to
their potential in predicting healthspan and application in age-related illnesses, such as …

Background DNA methylation changes at a discrete set of sites in the human genome are
predictive of chronological and biological age. However, it is not known whether these …

Epigenetic alterations are a hallmark of aging and age‐related diseases. Computational
models using DNA methylation data can create “epigenetic clocks” which are proposed to …

Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure
subject age. These clocks are acknowledged as a highly accurate molecular correlate of …