Polymer-based eye drops are the most used drug delivery system to treat dry eye disease
(DED). Therefore, the mucoadhesion between the polymer and the ocular mucin is crucial to …

A series of prospective ophthalmic vehicles based on hyaluronic acid (HA) and on
polyacrylic acid (PAA)(solutions, gels, matrices prepared by compression and by casting) …

Hyaluronan (HA) is frequently incorporated in eye drops to extend the pre-corneal residence
time, due to its viscosifying and mucoadhesive properties. Hydrodynamic and rheological …

Background: Dry eye–a disease affecting between 4 and 34% of the population worldwide.
Stressful conditions to ocular surface, contact lenses as well as systemic disease cause dry …

The aim of this work was to design and characterize cross-linked hyaluronic acid (HA)–
itaconic acid (IT) films loaded with dexamethasone sodium phosphate salt (DEX) for topical …

Hyaluronic acid (HA) is frequently formulated in eye drops to improve the stability of the tear
film by hydration and lubrication. Mucoadhesion is related to the ocular residence time and …

Dry eye syndrome and allergic conjunctivitis are the most common inflammatory disorders of
the eye surface. Although eye drops are the most usual prescribed dosage form, they are …

Films and microspheres were prepared from various esters of hyaluronic acid. A model drug,
methylprednisolone, was either physically incorporated into the polymer matrix or chemically …

Hyaluronan (HA) is widely used for eye drops as lubricant to counteract dry eye disease.
High and low molecular weight HA are currently used in ophthalmology. However, a large …

Hyaluronic acid (HA) and its derivatives play important roles in many fields of therapy, such
as arthritis treatment, plastic surgery, dermatology, otology, ophthalmology, etc. With a view …