Objective: To determine the associations of KIR3DL1/S1 (3DL1/S1) and its epistatic
interactions with human leukocyte antigen class I (HLA-I) alleles with resistance and …

Objectives: Coexpression of certain combinations of natural killer cell receptor KIR3DL1 and
HLA-B alleles is associated with slower time to AIDS. The strongest protection in terms of …

Genetic studies on the association of the killer immunoglobulin-like receptor (KIR) genes
with HIV-1 infection and disease progression have been widely carried out with somewhat …

Abstract Background Killer-cell Immunoglobulin-like Receptors (KIR) interact with Human
Leukocyte Antigen (HLA) to modify natural killer-and T-cell function. KIR are implicated in …

The human immunodeficiency virus (HIV) belongs to the Retroviridae family and remains a
public health problem in sub‐Saharan Africa. Recent reports from WHO have shown that 33 …

Killer cell immunoglobulin-like receptors (KIR) are the most polymorphic receptors of natural
killer (NK) cells. Their activity diversifies the functions of NK cells in the antiviral immune …

Several combinations of genes encoding KIR3DL1 alleles and their HLA-Bw4 ligands have
been linked with favorable outcomes upon exposure to or infection with human …

Background Genetic involvement of Killer Immunoglobulin-like Receptor (KIR)
polymorphisms and Human Immunodeficiency Virus (HIV)-exposed seronegative (HESN) …

Natural killer (NK) cells play a role in the clearance of viral infections. Combinations of
alleles at the polymorphic HLA-B locus and the NK cell surface killer immunoglobulin-like …

Objectives: Natural killer (NK) cell activity is increased in individuals who remain uninfected
despite repeated exposures to HIV. Given that a combined major histocompatibility complex …