Clostridium difficile infection: an immunological conundrum

R Arredondo-Hernandez, P Orduna-Estrada… - Archives of Medical …, 2018 - Elsevier
The lack of comprehensive understanding of the way immunity backfires on incidence and
complications has made Clostridium difficile infection (CDI), the infectious disease of our …

The host immune response to Clostridium difficile infection

K Solomon - Therapeutic advances in infectious disease, 2013 - journals.sagepub.com
Clostridium difficile infection (CDI) is the most common infectious cause of healthcare-
acquired diarrhoea. Outcomes of C. difficile colonization are varied, from asymptomatic …

Role of Microbiota and Innate Immunity in Recurrent Clostridium difficile Infection

S Bibbò, LR Lopetuso, G Ianiro… - Journal of …, 2014 - Wiley Online Library
Recurrent Clostridium difficile infection represents a burdensome clinical issue whose
epidemiology is increasing worldwide. The pathogenesis is not yet completely known …

Clostridium difficile infection

WK Smits, D Lyras, DB Lacy, MH Wilcox… - Nature reviews Disease …, 2016 - nature.com
Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life
threatening, especially in elderly people and in patients who have dysbiosis of the gut …

Neutrophil-mediated inflammation in the pathogenesis of Clostridium difficile infections

S Jose, R Madan - Anaerobe, 2016 - Elsevier
Clostridium difficile is the most important cause of nosocomial infectious diarrhea in the
western world. C. difficile infections are a major healthcare burden with approximately …

The inflammasome and type-2 immunity in Clostridium difficile infection

A Donlan, WA Petri Jr - Clinics in colon and rectal surgery, 2020 - thieme-connect.com
Clostridium difficile (reclassified as “Clostridioides”) is the leading cause of hospital-
acquired infections in the United States, and is associated with high-patient mortality and …

The host immune response to Clostridium difficile

CP Kelly, L Kyne - Journal of medical microbiology, 2011 - microbiologyresearch.org
Clostridium difficile is the most common cause of nosocomial bacterial diarrhoea in the
Western world. Diarrhoea and colitis are caused by the actions of toxins A and B released by …

Immune responses induced by Clostridium difficile

S Péchiné, A Collignon - Anaerobe, 2016 - Elsevier
The spectrum of Clostridium difficile infections is highly variable, ranging from asymptomatic
carriage to fatal colitis depending on the strain virulence and on the host, its gut microbiota …

Immune responses to Clostridium difficile infection

R Madan, WA Petri Jr - Trends in molecular medicine, 2012 - cell.com
Clostridium difficile is the causal agent of antibiotic-associated diarrhea and is a leading
cause of hospital-acquired infections in the US. C. difficile has been known to cause severe …

[HTML][HTML] Clostridium difficile Infection and the Role of Adaptive Immunity in the Microbiome

M Fischer - Gastroenterology & Hepatology, 2017 - ncbi.nlm.nih.gov
MF Clostridium difficile infection usually occurs in sus ceptible patients after antibiotic
therapy kills a good por tion of the native microbiota. In these vulnerable individ uals, when …