[HTML][HTML] Synaptopathology involved in autism spectrum disorder

S Guang, N Pang, X Deng, L Yang, F He… - Frontiers in cellular …, 2018 - frontiersin.org
Autism spectrum disorder (ASD) encompasses a group of multifactorial neurodevelopmental
disorders characterized by impaired social communication, social interaction and repetitive …

A synaptic trek to autism

T Bourgeron - Current opinion in neurobiology, 2009 - Elsevier
Autism spectrum disorders (ASD) are diagnosed on the basis of three behavioral features
namely deficits in social communication, absence or delay in language, and stereotypy. The …

Synaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities

HY Zoghbi, MF Bear - Cold Spring Harbor perspectives …, 2012 - cshperspectives.cshlp.org
The discovery of the genetic causes of syndromic autism spectrum disorders and intellectual
disabilities has greatly informed our understanding of the molecular pathways critical for …

[HTML][HTML] Synaptic proteins and receptors defects in autism spectrum disorders

J Chen, S Yu, Y Fu, X Li - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Recent studies have found that hundreds of genetic variants, including common and rare
variants, rare and de novo mutations, and common polymorphisms contribute to the …

[HTML][HTML] GABAergic system dysfunction in autism spectrum disorders

H Zhao, X Mao, C Zhu, X Zou, F Peng… - Frontiers in cell and …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) refers to a series of neurodevelopmental diseases
characterized by two hallmark symptoms, social communication deficits and repetitive …

Behavioral neuroscience of autism

T Takumi, K Tamada, F Hatanaka, N Nakai… - … & Biobehavioral Reviews, 2020 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder. Several genetic causes
of ASD have been identified and this has enabled researchers to construct mouse models …

Characterizing autism spectrum disorders by key biochemical pathways

M Subramanian, CK Timmerman, JL Schwartz… - Frontiers in …, 2015 - frontiersin.org
The genetic and phenotypic heterogeneity of autism spectrum disorders (ASD) presents a
substantial challenge for diagnosis, classification, research, and treatment. Investigations …

Autism and the synapse: emerging mechanisms and mechanism-based therapies

D Ebrahimi-Fakhari, M Sahin - Current opinion in neurology, 2015 - journals.lww.com
Identifying converging pathways in syndromic forms of ASD will uncover novel therapeutic
targets for non-syndromic ASD. Insights into developmental synaptopathies will lead to …

[HTML][HTML] Genetic aspects of autism spectrum disorders: insights from animal models

S Banerjee, M Riordan, MA Bhat - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Autism spectrum disorders (ASDs) are a complex neurodevelopmental disorder that display
a triad of core behavioral deficits including restricted interests, often accompanied by …

[HTML][HTML] Fundamental elements in autism: from neurogenesis and neurite growth to synaptic plasticity

J Gilbert, HY Man - Frontiers in cellular neuroscience, 2017 - frontiersin.org
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders with a high
prevalence and impact on society. ASDs are characterized by deficits in both social behavior …