The effect of inkjet printing over polymeric films as potential buccal biologics delivery systems

M Montenegro-Nicolini, PE Reyes, MO Jara… - AAPS …, 2018 - Springer
The buccal mucosa appears as a promissory route for biologic drug administration, and
pharmaceutical films are flexible dosage forms that can be used in the buccal mucosa as …

Inkjet printing of a thermolabile model drug onto FDM-printed substrates: formulation and evaluation

GK Eleftheriadis, CS Katsiotis… - Drug Development …, 2020 - Taylor & Francis
Objective The inkjet printing (IP) and fused deposition modeling (FDM) technologies have
emerged in the pharmaceutical field as novel and personalized formulation approaches …

Overview and future potential of buccal mucoadhesive films as drug delivery systems for biologics

M Montenegro-Nicolini, JO Morales - AAPS PharmSciTech, 2017 - Springer
The main route of administration for drug products is the oral route, yet biologics are initially
developed as injectables due to their limited stability through the gastrointestinal tract and …

Buccal delivery of small molecules and biologics: of mucoadhesive polymers, films, and nanoparticles–an update

VV Nair, P Cabrera, C Ramírez-Lecaros… - International Journal of …, 2023 - Elsevier
Buccal delivery of small and large molecules is an attractive route of administration that has
been studied extensively over the past few decades. This route bypasses first-pass …

[HTML][HTML] Development and characterization of inkjet printed edible films for buccal delivery of B-complex vitamins

G Eleftheriadis, PK Monou, E Andriotis, E Mitsouli… - Pharmaceuticals, 2020 - mdpi.com
Buccal films containing two vitamins, ie, thiamine hydrochloride (THCl) and nicotinic acid
(NA), were fabricated via two-dimensional (2D) inkjet printing. For the preparation of buccal …

Fabrication of mucoadhesive buccal films for local administration of ketoprofen and lidocaine hydrochloride by combining fused deposition modeling and inkjet …

GK Eleftheriadis, PK Monou, N Bouropoulos… - Journal of …, 2020 - Elsevier
In the area of developing oromucosal drug delivery systems, mucoadhesive buccal films are
the most promising formulations for either systemic or local drug delivery. The current study …

Development of oromucosal dosage forms by combining electrospinning and inkjet printing

M Palo, K Kogermann, I Laidmae, A Meos… - Molecular …, 2017 - ACS Publications
Printing technology has been shown to enable flexible fabrication of solid dosage forms for
personalized drug therapy. Several methods can be applied for tailoring the properties of the …

[HTML][HTML] In vitro evaluation of 2D-printed edible films for the buccal delivery of diclofenac sodium

GK Eleftheriadis, PK Monou, N Bouropoulos… - Materials, 2018 - mdpi.com
Printing technologies have recently emerged in the development of novel drug delivery
systems toward personalized medicine, to improve the performance of formulations, existing …

Unidirectional drug release from 3D printed mucoadhesive buccal films using FDM technology: In vitro and ex vivo evaluation

GK Eleftheriadis, C Ritzoulis, N Bouropoulos… - European Journal of …, 2019 - Elsevier
Oromucosal delivery of active pharmaceutical ingredients provides an attractive alternative
route of administration, due to avoidance of the first pass effect and improved patient …

Inkjet printing of proteins: an experimental approach

M Montenegro-Nicolini, V Miranda, JO Morales - The AAPS journal, 2017 - Springer
Peptides and proteins represent a promissory group of molecules used by the
pharmaceutical industry for drug therapy with great potential for development. However, the …