HLA class I and II alleles in susceptibility to ankylosing spondylitis
JD Reveille, X Zhou, MJ Lee, MH Weisman… - Annals of the …, 2019 - ard.bmj.com
Objective To examine associations of HLA class I and class II alleles with ankylosing
spondylitis (AS) in three cohorts of patients of European, Asian and African ancestry …
spondylitis (AS) in three cohorts of patients of European, Asian and African ancestry …
Construction and benchmarking of a multi-ethnic reference panel for the imputation of HLA class I and II alleles
F Degenhardt, M Wendorff, M Wittig… - Human molecular …, 2019 - academic.oup.com
Genotype imputation of the human leukocyte antigen (HLA) region is a cost-effective means
to infer classical HLA alleles from inexpensive and dense SNP array data. In the research …
to infer classical HLA alleles from inexpensive and dense SNP array data. In the research …
The ties that bind: skin, gut and spondyloarthritis
E Gracey, E Dumas, M Yerushalmi… - Current Opinion in …, 2019 - journals.lww.com
The ties that bind: skin, gut and spondyloarthritis : Current Opinion in Rheumatology The ties
that bind: skin, gut and spondyloarthritis : Current Opinion in Rheumatology Log in or Register …
that bind: skin, gut and spondyloarthritis : Current Opinion in Rheumatology Log in or Register …
Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians
Human leukocyte antigen (HLA) is a key genetic factor conferring risk of systemic lupus
erythematosus (SLE), but precise independent localization of HLA effects is extremely …
erythematosus (SLE), but precise independent localization of HLA effects is extremely …
FMF is associated with a wide spectrum of MHC class I-and allied SpA disorders but not with classical MHC class II-associated autoimmune disease: insights from a …
Objectives: To test the hypothesis that familial Mediterranean fever (FMF)-associated
autoinflammation may exaggerate the tendency toward adaptive immunopathology or …
autoinflammation may exaggerate the tendency toward adaptive immunopathology or …
Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus triggered
by immune hypersensitivity to food. Herein, we tested whether genetic risk factors for known …
by immune hypersensitivity to food. Herein, we tested whether genetic risk factors for known …
Does MHC heterozygosity influence microbiota form and function?
MHC molecules are essential for the adaptive immune response, and they are the most
polymorphic genetic loci in vertebrates. Extreme genetic variation at these loci is paradoxical …
polymorphic genetic loci in vertebrates. Extreme genetic variation at these loci is paradoxical …
Additive and heterozygous (dis)advantage GWAS models reveal candidate genes involved in the genotypic variation of maize hybrids to Azospirillum brasilense
Maize genotypes can show different responsiveness to inoculation with Azospirillum
brasilense and an intriguing issue is which genes of the plant are involved in the recognition …
brasilense and an intriguing issue is which genes of the plant are involved in the recognition …
the genetics of the human leucocyte antigen region in inflammatory bowel disease
JJ Ashton, K Latham, RM Beattie… - Alimentary …, 2019 - Wiley Online Library
Background The human leucocyte antigen (HLA) complex, located at chromosome 6p21. 3
is a highly polymorphic region containing the classical class I and II HLA genes. The region …
is a highly polymorphic region containing the classical class I and II HLA genes. The region …
Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women
K Lawrenson, F Song, DJ Hazelett, SP Kar, J Tyrer… - Gynecologic …, 2019 - Elsevier
Objective Genome-wide association studies (GWASs) for epithelial ovarian cancer (EOC)
have focused largely on populations of European ancestry. We aimed to identify common …
have focused largely on populations of European ancestry. We aimed to identify common …