Emerging evidence demonstrates that microRNAs, as important endogenous
posttranscriptional regulators, are essential for bone remodeling and regeneration …

Skeletal diseases normally represents a grievous imbalance between osteoblasts for bone
formation and osteoclasts for bone resorption. A lack of osteogenic function can make it …

ABSTRACT Preclinical Research Bone is a rigid and dynamic organ that undergoes
continuous turnover. Bone homeostasis is maintained by osteoclast‐mediated bone …

MicroRNAs are small, noncoding single-stranded RNAs that have emerged as important
posttranscriptional regulators of gene expression, with an essential role in vertebrate …

Abstract Purpose of Review The small non-coding microRNAs (miRNAs) have emerged as
important post-transcriptional regulators of various physiological and pathological …

Bone has multiple functions, both morphologically and physiologically, and it frequently
features in the pathological condition, including fracture and osteoporosis. For bone …

MicroRNAs (miRNAs) are a class of small (20–24 nucleotides), highly conserved, non-
coding RNA molecules whose main function is the post-transcriptional regulation of gene …

Osteoblast differentiation and bone formation (osteogenesis) are regulated by transcriptional
and post-transcriptional mechanisms. Recently, a novel class of regulatory factors termed …

Highlights•Aberrant miRNA expression has emerged as an important pathomechanism in
various human diseases, including osteoporosis.•The 'Off-target effects' is one of the most …

Osteoclast-mediated bone resorption is responsible for bone metabolic diseases, negatively
impacting people's health and life. It has been demonstrated that microRNA influences the …