[PDF][PDF] SIRT1-Dependent Upregulation of Antiglycative Defense in HUVECs Is Essential for Resveratrol Protection against High Glucose Stress

V Dolo, S Falone, F Amicarelli - researchgate.net
Uncontrolled accumulation of methylglyoxal (MG) and reactive oxygen species (ROS)
occurs in hyperglycemia-induced endothelial dysfunction associated with diabetes …

[HTML][HTML] SIRT1-dependent upregulation of antiglycative defense in HUVECs is essential for resveratrol protection against high glucose stress

SJ Santini, V Cordone, M Mijit, V Bignotti, P Aimola… - Antioxidants, 2019 - mdpi.com
Uncontrolled accumulation of methylglyoxal (MG) and reactive oxygen species (ROS)
occurs in hyperglycemia-induced endothelial dysfunction associated with diabetes …

SIRT1-DEPENDENT CYTOPROTECTIVE EFFECTS OF RESVERATROL IN HIGH GLUCOSE-CHALLENGED HUMAN ENDOTHELIAL CELLS INVOLVES …

M Mijiti - 2020 - research.unite.it
Overproduction of methylglyoxal (MG) and reactive oxygen species (ROS) occurs in
hyperglycemia-induced endothelial dysfunction associated with diabetes. Resveratrol (RSV) …

[PDF][PDF] SIRT1-dependent response is crucial for the resveratrolinduced upregulation of antioxidant and antiglycative defence in high glucose-challenged HUVECs

M Mijiti, SS Junior, C Valeria, V Bignotti… - FEBS3+ LS2 annual …, 2020 - research.unite.it
Excessive accumulation of reactive oxygen species (ROS) and unrestrained build-up of
glycolysis-derived methlyglyoxal (MG) are thought to be involved in the endothelial …

Ginsenoside Rd ameliorates high glucose-induced retinal endothelial injury through AMPK-STRT1 interdependence

K Tang, W Qin, R Wei, Y Jiang, L Fan, Z Wang… - Pharmacological …, 2022 - Elsevier
Diabetic retinopathy (DR) manifests as a complicated and blinding complication in diabetes
mellitus. First-line treatments for advanced DR have shown ocular side-effects in some …

Metformin modulates hyperglycemia‐induced endothelial dysfunction through SIRT1

G Arunachalam, SM Samuel, H Ding, CR Triggle - 2013 - Wiley Online Library
Endothelial dysfunction, detected at an early stage in the development of diabetes‐related
microvascular disease, is associated with accelerated endothelial senescence …

Resveratrol up-regulates SIRT1 and inhibits cellular oxidative stress in the diabetic milieu: mechanistic insights

JM Yun, A Chien, I Jialal, S Devaraj - The Journal of nutritional …, 2012 - Elsevier
Several lines of evidence support a role for oxidative stress in diabetic complications.
Diabetic patients have increased O2− production in monocytes. Loss of SIRT1 activity may …

[HTML][HTML] Resveratrol regulates insulin resistance to improve the glycolytic pathway by activating SIRT2 in PCOS granulosa cells

A Liang, W Zhang, Q Wang, L Huang, J Zhang… - Frontiers in …, 2023 - frontiersin.org
Scope Insulin resistance (IR) has a close relationship with the main clinical manifestations of
patients with PCOS; hence, the research and development of new drugs to treat PCOS by …

Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells

Z Ungvari, P Mukhopadhyay, P Pacher… - The FASEB …, 2010 - Wiley Online Library
Production of hyperglycemia‐induced mitochondrial reactive oxygen species (mtROS) is a
key event in the development of diabetic complications. Because resveratrol, a naturally …

[HTML][HTML] Multi-targeted mechanisms underlying the endothelial protective effects of the diabetic-safe sweetener erythritol

DM Boesten, A Berger, P de Cock, H Dong… - PLoS …, 2013 - journals.plos.org
Diabetes is characterized by hyperglycemia and development of vascular pathology.
Endothelial cell dysfunction is a starting point for pathogenesis of vascular complications in …