Why genome-wide associations with cognitive ability measures are probably spurious
K Richardson, MC Jones - New Ideas in Psychology, 2019 - Elsevier
Much time and effort, as well as funding, is being devoted to Genome Wide Association
Studies (GWAS) for identifying genetic causes of variation (single nucleotide polymorphisms …
Studies (GWAS) for identifying genetic causes of variation (single nucleotide polymorphisms …
Results of a “GWAS plus:” general cognitive ability is substantially heritable and massively polygenic
We carried out a genome-wide association study (GWAS) for general cognitive ability (GCA)
plus three other analyses of GWAS data that aggregate the effects of multiple single …
plus three other analyses of GWAS data that aggregate the effects of multiple single …
[HTML][HTML] Evidence for recent polygenic selection on educational attainment and intelligence inferred from Gwas hits: A replication of previous findings using recent data
D Piffer - Psych, 2019 - mdpi.com
Genetic variants identified by three large genome-wide association studies (GWAS) of
educational attainment (EA) were used to test a polygenic selection model. Weighted and …
educational attainment (EA) were used to test a polygenic selection model. Weighted and …
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Here we conducted a large-scale genetic association analysis of educational attainment in a
sample of approximately 1.1 million individuals and identify 1,271 independent genome …
sample of approximately 1.1 million individuals and identify 1,271 independent genome …
[HTML][HTML] Gene discovery and polygenic prediction from a 1.1-million-person GWAS of educational attainment
We conduct a large-scale genetic association analysis of educational attainment in a sample
of~ 1.1 million individuals and identify 1,271 independent genome-wide-significant SNPs …
of~ 1.1 million individuals and identify 1,271 independent genome-wide-significant SNPs …
Educational attainment: a genome wide association study in 9538 Australians
Background Correlations between Educational Attainment (EA) and measures of cognitive
performance are as high as 0.8. This makes EA an attractive alternative phenotype for …
performance are as high as 0.8. This makes EA an attractive alternative phenotype for …
A three-stage genome-wide association study of general cognitive ability: hunting the small effects
Childhood general cognitive ability (g) is important for a wide range of outcomes in later life,
from school achievement to occupational success and life expectancy. Large-scale …
from school achievement to occupational success and life expectancy. Large-scale …
Predicting educational achievement from DNA
A genome-wide polygenic score (GPS), derived from a 2013 genome-wide association
study (N= 127,000), explained 2% of the variance in total years of education (EduYears). In …
study (N= 127,000), explained 2% of the variance in total years of education (EduYears). In …
Replicability and robustness of genome-wide-association studies for behavioral traits
A recent genome-wide-association study of educational attainment identified three single-
nucleotide polymorphisms (SNPs) whose associations, despite their small effect sizes (each …
nucleotide polymorphisms (SNPs) whose associations, despite their small effect sizes (each …
Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction
Little is known about the genetic architecture of traits affecting educational attainment other
than cognitive ability. We used genomic structural equation modeling and prior genome …
than cognitive ability. We used genomic structural equation modeling and prior genome …