Heart failure with preserved ejection fraction and adipose tissue: a story of two tales

A Oh, R Okazaki, F Sam… - Frontiers in Cardiovascular …, 2019 - frontiersin.org
Heart failure with preserved ejection fraction (HFpEF) is characterized by signs and
symptoms of heart failure in the presence of a normal left ventricular ejection fraction …

Obesity and heart failure with preserved ejection fraction: new insights and pathophysiological targets

BA Borlaug, MD Jensen, DW Kitzman… - Cardiovascular …, 2022 - academic.oup.com
Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …

Obesity-related heart failure with preserved ejection fraction: pathophysiology, diagnosis, and potential therapies

T Harada, M Obokata - Heart failure clinics, 2020 - heartfailure.theclinics.com
Heart failure (HF) is a widespread public health problem with increasing burdens of
morbidity, mortality, and health care costs. As of 2018, approximately 6.5 million American …

Obesity in Heart Failure with Reduced Ejection Fraction: Time to Address the Elephant in the Room

MB Amdahl, V Sundaram… - Cardiology Clinics, 2023 - cardiology.theclinics.com
The prevalence of obesity is rapidly increasing in the Western World, and by 2030, it is
estimated that one out of two adults in the United States will be obese. 1 Obesity is clearly …

Obesity and heart failure with preserved ejection fraction

E Koutroumpakis, R Kaur… - Heart Failure …, 2021 - heartfailure.theclinics.com
At present, heart failure with preserved ejection fraction (HFpEF) accounts for more than half
of the heart failure (HF) diagnoses in the community. 1–3 Its prevalence has been …

Obesity and heart failure with preserved ejection fraction: a paradox or something else?

M Tadic, C Cuspidi - Heart failure reviews, 2019 - Springer
Obesity represents one of the most common comorbidities in patients with heart failure and
preserved ejection fraction (HFpEF). Studies have shown that obesity is not only a …

Obesity and heart failure with preserved ejection fraction: A growing problem

SB Prenner, PJ Mather - Trends in Cardiovascular Medicine, 2018 - Elsevier
Abstract Heart Failure with Preserved Ejection Fraction (HFpEF) is increasing in prevalence
due to the aging of the United States population as well as the current obesity epidemic …

Connecting epicardial adipose tissue and heart failure with preserved ejection fraction: mechanisms, management and modern perspectives

G van Woerden, DJ van Veldhuisen… - European Journal of …, 2022 - Wiley Online Library
Obesity is very common in patients with heart failure with preserved ejection fraction
(HFpEF) and it has been suggested that obesity plays an important role in the …

Disparate effects of obesity on survival and hospitalizations in heart failure with preserved ejection fraction

S Carbone, CJ Lavie - International Journal of Obesity, 2020 - nature.com
Obesity is a major risk factor for heart failure (HF), predominantly HF with preserved ejection
fraction (HFpEF). The increased risk of HF associated with obesity have been recently …

Evidence supporting the existence of a distinct obese phenotype of heart failure with preserved ejection fraction

M Obokata, YNV Reddy, SV Pislaru, V Melenovsky… - Circulation, 2017 - Am Heart Assoc
Background: Heart failure (HF) with preserved ejection fraction (HFpEF) is a heterogeneous
syndrome. Phenotyping patients into pathophysiologically homogeneous groups may …