[HTML][HTML] No interaction between childhood maltreatment and serotonin transporter gene in recurrent major depressive disorder: a clinical sample
G Özçürümez, HT Yurdakul, Y Terzi… - Archives of …, 2019 - ncbi.nlm.nih.gov
Methods: Participants included a well-characterized clinical sample of 70 recurrent MDD
cases and 67 never psychiatrically ill controls, aged 18 years or over. Socio-demographic …
cases and 67 never psychiatrically ill controls, aged 18 years or over. Socio-demographic …
Interaction between specific forms of childhood maltreatment and the serotonin transporter gene (5-HTT) in recurrent depressive disorder
BACKGROUND: There is inconsistent evidence of interaction between stressful events and
a serotonin transporter promoter polymorphism (5-HTTLPR) in depression. Recent studies …
a serotonin transporter promoter polymorphism (5-HTTLPR) in depression. Recent studies …
Serotonin transporter length polymorphism, childhood maltreatment, and chronic depression: a specific gene–environment interaction
GW Brown, M Ban, TKJ Craig, TO Harris… - Depression and …, 2013 - Wiley Online Library
Background Key questions about the interaction between the serotonin transporter length
polymorphism (5‐HTTLPR) and stress in the etiology of depression remain unresolved. We …
polymorphism (5‐HTTLPR) and stress in the etiology of depression remain unresolved. We …
Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving …
BACKGROUND: Genetic and environmental factors shape life-long vulnerability to
depression, but most gene–environment interaction (G× E) research has focused on cross …
depression, but most gene–environment interaction (G× E) research has focused on cross …
Serotonin transporter polymorphism (5HTTLPR), severe childhood abuse and depressive symptom trajectories in adulthood
TB Nguyen, JM Gunn, M Potiriadis, IP Everall… - BJPsych …, 2015 - cambridge.org
BackgroundCross-sectional studies suggest that the serotonin transporter promoter region
polymorphism (5-HTT gene-linked polymorphic region, 5HTTLPR) moderates the …
polymorphism (5-HTT gene-linked polymorphic region, 5HTTLPR) moderates the …
Moderation of adult depression by the serotonin transporter promoter variant (5‐HTTLPR), childhood abuse and adult traumatic events in a general population sample
HJ Grabe, C Schwahn, J Mahler… - American Journal of …, 2012 - Wiley Online Library
The impact of the promoter polymorphisms of the serotonin transporter (5‐HTTLPR) on
mood has been studied by two‐way interaction models comprising one environmental factor …
mood has been studied by two‐way interaction models comprising one environmental factor …
Depression and the serotonin transporter 5-HTTLPR polymorphism: a review and a hypothesis concerning gene–environment interaction
GW Brown, TO Harris - Journal of affective disorders, 2008 - Elsevier
Studies of the interaction of the serotonin transporter genotype and environment upon adult
depression (G× E) have suggested a role for both childhood maltreatment and stressful life …
depression (G× E) have suggested a role for both childhood maltreatment and stressful life …
Contributions of maltreatment and serotonin transporter genotype to depression in childhood, adolescence, and early adulthood
BACKGROUND: Past findings on gene-by-environment (G× E) effects on depression have
been mixed, leading to a debate of the plausibility of such mechanisms and methodological …
been mixed, leading to a debate of the plausibility of such mechanisms and methodological …
Reported childhood abuse is associated with low serotonin transporter binding in vivo in major depressive disorder
Background: Physical or psychological adversity in childhood is associated with a higher
risk for depression in adulthood, and with persistent serotonergic abnormalities in humans …
risk for depression in adulthood, and with persistent serotonergic abnormalities in humans …
Association of Adverse Childhood Environment and 5-HTTLPR Genotype With Late-Life Depression
K Ritchie, I Jaussent, R Stewart, AM Dupuy… - The Journal of clinical …, 2009 - psychiatrist.com
Objective: Neurobiological and clinical studies suggest that childhood maltreatment may
result in functional and structural nervous system changes that predispose the individual to …
result in functional and structural nervous system changes that predispose the individual to …