Research suggests that genetic variants linked to hypothalamic-pituitary-adrenal (HPA)-axis
functioning moderate the association between environmental stressors and depression, but …

Childhood adversity appears to sensitize youth to stress, increasing depression risk
following stressful life events occurring throughout the lifespan. Some evidence suggests …

Based on a multiwave, two-year prospective design, this study is the first to examine the
extent to which multilocus hypothalamic–pituitary–adrenal axis (HPA axis)-related genetic …

Background Despite a growing body of evidence showing both genetic and environmental
influences on adolescent depression and anxiety, the involved comorbid mechanisms …

Research suggests that childhood adversity (CA) is associated with a wide range of
repercussions, including an increased likelihood of interpersonal stress generation. This …

Background: Genetic risks for depression may be expressed through greater exposure
towards environmental stressors (gene–environment correlation, rGE) and increased …

Research suggests that genetic variants that regulate the hypothalamic-pituitary-adrenal
(HPA) axis function moderate the association between parenting and anxiety symptoms, but …

Familial risk for depression is associated with youth exposure to self-generated dependent
stressful life events and independent events that are out of youth's control. Familial risk …

Serotonin-linked genetic risk and stressful life event (SLE) interaction research has been
criticized for using single genetic variants with inconsistent replicability. A recent study …

Although offspring of depressed mothers are at an increased risk for depression themselves,
not all of these children develop depression, highlighting the need to identify specific …