Neurodegenerative diseases are typified by neuronal loss associated with progressive
dysfunction and clinical presentation. Neurodegenerative diseases are characterized by the …

Neurodegenerative diseases are the second most common cause of death and
characterized by progressive impairments in movement or mental functioning in the central …

Prevention of neurodegenerative diseases is presently a major goal for our Society and
melatonin, an unusual phylogenetically conserved molecule present in all aerobic …

Neural aging as a progressive loss of function involves central and peripheral postmitotic
neurons and neural stem cells (NSCs). It promotes neurodegeneration, impairs …

Neurodegeneration is the hallmark of many chronic progressive neurogical disorders
characterized by specific clinical, morphological and biochemical features. Central nervous …

Melatonin, a pineal gland synthesized neurohormone is known as a multifunctioning
pleiotropic agent which has a wide range of neuroprotective role in manifold age-related …

Melatonin is an indolamine with a large spectrum of functions that can be divided into
chronobiotic and nonchronobiotic. Chronobiotic effects are mediated by the daily rhythm of …

Melatonin is produced and released by the pineal gland in a circadian rhythm. This
neurohormone has proven to be an antioxidant and anti-inflammatory molecule able to …

In many psychiatric, neurodegenerative and systemic inflammatory disorders circadian
melatonin is decreased whilst melatonin enzymes and melatonin receptors are genetic …

Melatonin treatment showed a potent neuroprotective action in experimental models and in
clinical studies. However, the entire disease prevention is not observed with melatonin …