Abstract Embryonic Stem Cells (ESCs) uniquely stand out amidst other known cellular models due to their remarkable properties of self-renewal and pluripotency. Due to the …
Cell division is a tightly coordinated process that involves doubling of the cellular content and its separation into two genetically identical daughter cells. In G1 phase of the cell cycle …
DNA sequences that regulate gene expression are marked by distinct chromatin architectures that segregate these functional elements from the surrounding genome. In …
Abstract While the Nuclear Pore Complex's (NPC) canonical function is to act as a selective barrier across the Nuclear Envelope (NE) and regulate nucleocytoplasmic traffic, recent …
Sixty-one analogs of benzoylsulfonohydrazides were subjected to 3D QSAR studies using CoMFA and CoMSIA techniques followed by docking studies to develop a correlation of the …
Epigenetics is a young study field which evolved in the 1950s. Nowadays it is becoming more and more important, even crucial, component of biology. Epigenetic modifications …
La Cardiomiopatia Aritmogena (ACM) è una malattia genetica dovuta alla presenza di mutazioni in geni desmosomali, con bassa penetranza ed espressività variabile. Dal punto …
Atherosklerose, eine chronisch-inflammatorische und fibroproliferative Erkrankung der arteriellen Gefäße, und deren klinische Krankheitsmanifestationen wie Herzinfarkt oder …
Abstract Duchenne Muscular Dystrophy (DMD) is a lethal disease caused by mutations in the Dystrophin gene. DMD is characterized by continuous cycles of muscle contraction …