Environmental enrichment (EE) is an experimental paradigm that is used to explore how a
complex, stimulating environment can impact overall health. In laboratory animal …

Young blood plasma is known to confer beneficial effects on various organs in mice.
However, it was not known whether young plasma rejuvenates cells and tissues at the …

Biological aging reflects decline in physiological functions and is an effective indicator of
morbidity and mortality. Numerous epigenetic age calculators are available, however …

DNA methylation is an epigenetic mark with important regulatory roles in cellular identity and
can be quantified at base resolution using bisulfite sequencing. Most studies are limited to …

The number of elderly persons is rising rapidly, and healthspan is a key factor in determining
the well-being of individuals and the sustainability of national health systems. Environmental …

Social epigenomics has emerged as an integrative field of research focused on identification
of socio-environmental factors, their influence on human biology through epigenomic …

Recent advances in DNA sequencing technologies have enhanced our knowledge about
several diseases. Coupled with easy accessibility to blood samples, hematology plays a …

Objectives Epigenetic modifications are closely linked with aging, but their relationship with
cognition remains equivocal. Given known sex differences in epigenetic aging, we explored …

DNA methylation (DNAm) is shaped by genetic and environmental factors and modulated by
aging. Here, we examine interrelations between epigenetic aging, body weight (BW), and …

Several DNA methylation clocks have been developed to reflect chronological age of human
tissues, but most clocks have been trained on adult samples. The rapid methylome changes …