Reproductive biology is a uniquely important topic since it is about germ cells, which are
central for transmitting genetic information from generation to generation. In this review, we …

Epigenetic modifications, including DNA methylation and histone modifications, are
reprogrammed considerably following fertilization during mammalian early embryonic …

The molecular mechanism regulating embryo development under reduced oxygen tension
remains elusive. This study aimed to identify the molecular mechanism impacting embryo …

Background Zebrafish is a popular model organism, which is widely used in developmental
biology research. Despite its general use, the direct comparison of the zebrafish and human …

Background Preimplantation embryo development is a highly ordered sequence of
processes and it requires a precise temporal and spatial control of gene expression …

Although the role of translocator protein (TSPO) in cholesterol transport in steroid-
synthesizing cells has been studied extensively, recent studies of TSPO genetic depletion …

Motivation Single-cell RNA-sequencing (scRNA-seq) has become an important tool to
unravel cellular heterogeneity, discover new cell (sub) types, and understand cell …

A key step in trajectory inference is the determination of starting cells, which is typically done
by using manually selected marker genes. In this study, we find that the quantile polarization …

Decidualization is a critical process for successful embryo implantation and subsequent
placenta formation. The characterization and physiological function of long non-coding RNA …

Variation and heterogeneity between cells are the basic characteristics of stem cells.
Traditional sequencing analysis methods often cover up this difference. Single-cell …