Transcription profiles of oocytes during maturation and embryos during preimplantation development in vivo in the goat

Y Li, J Sun, Y Ling, H Ming, Z Chen… - Reproduction …, 2020 - CSIRO Publishing
RNA sequencing performed on goat matured oocytes and preimplantation embryos
generated invivo enabled us to define the transcriptome for goat preimplantation embryo …

Methionine adenosyltransferase 2β participates in mouse oocyte maturation by regulating the MAPK pathway

Q An, H Sun, J Zhang, Z Lu, W Peng, S Xu… - Reproductive …, 2020 - Springer
The methionine adenosyltransferase 2β gene (Mat2b) encodes for the regulatory subunit of
methionine adenosyltransferase (MAT), which catalyzes the biosynthesis of S …

Cell population characterization and discovery using single-cell technologies in endocrine systems

LYM Cheung, K Rizzoti - Journal of Molecular Endocrinology, 2020 - jme.bioscientifica.com
In the last 15 years, single-cell technologies have become robust and indispensable tools to
investigate cell heterogeneity. Beyond transcriptomic, genomic and epigenome analyses …

Single‐cell sequencing of miRNAs: A modified technology

C Chakraborty, M Bhattacharya… - Cell Biology …, 2020 - Wiley Online Library
The recent development of next‐generation sequencing technologies has offered valuable
insights into individual cells. This technology is centered on the characterization of single …

Fatty acid metabolism as an indicator for the maternal–to–zygotic transition in porcine IVF embryos revealed by RNA sequencing

J Xiang, Y Xing, C Long, D Hou, F Liu, Y Zhang, Z Lu… - Theriogenology, 2020 - Elsevier
A number of fatty acids have been found in porcine oocytes and early embryos. Recent
studies have indicated the importance of fatty acids in the development of pre-implantation …

Coordinated analysis of exon and intron data reveals novel differential gene expression changes

HR Eghbalnia, WW Wilfinger, K Mackey… - Scientific Reports, 2020 - nature.com
RNA-Seq expression analysis currently relies primarily upon exon expression data. The
recognized role of introns during translation, and the presence of substantial RNA-Seq …

An experiment on ab initio discovery of biological knowledge from scRNA-Seq data using machine learning

N Shah, J Li, F Li, W Chen, H Gao, S Chen, K Hua… - Patterns, 2020 - cell.com
Expectations of machine learning (ML) are high for discovering new patterns in high-
throughput biological data, but most such practices are accustomed to relying on existing …

Whole-Transcriptome Sequencing-Based Analysis of DAZL and Its Interacting Genes during Germ Cells Specification and Zygotic Genome Activation in Chickens

D Rengaraj, S Won, JW Han, DA Yoo, H Kim… - International Journal of …, 2020 - mdpi.com
The deleted in azoospermia like (DAZL) is required for germ cells development and
maintenance. In chickens, the mRNA and protein of DAZL, a representative maternally …

Dusp4 contributes to anesthesia neurotoxicity via mediated neural differentiation in primates

J Yan, J Li, Y Cheng, Y Zhang, Z Zhou… - Frontiers in Cell and …, 2020 - frontiersin.org
Background Children who are exposed to anesthesia multiple times may undergo cognitive
impairment during development. The underlying mechanism has been revealed as …

Deep Transcriptomic Analysis Reveals the Dynamic Developmental Progression during Early Development of Channel Catfish (Ictalurus punctatus)

X Ma, B Su, Y Tian, NJC Backenstose, Z Ye… - International Journal of …, 2020 - mdpi.com
The transition from fertilized egg to larva in fish is accompanied with various biological
processes. We selected seven early developmental stages in channel catfish, Ictalurus …