Differential Immunogenicity and Protective Efficacy Elicited by MTO‐ and DMT‐Adjuvanted CMFO Subunit Vaccines against Mycobacterium tuberculosis Infection

N Ullah, L Hao, Y Wu, Y Zhang, Q Lei… - Journal of …, 2020 - Wiley Online Library
Tuberculosis (TB) remains a major and global problem of public health. An effective TB
subunit vaccine is urgently needed. Proper selection of the delivery system for the vaccine is …

Assessing trends in vaccine efficacy by pathogen genetic distance

D Benkeser, M Juraska, PB Gilbert - Journal de la société française de …, 2020 - numdam.org
Preventive vaccines are an effective public health intervention for reducing the burden of
infectious diseases, but have yet to be developed for several major infectious diseases …

[HTML][HTML] Anti-PfGARP kills parasites by inducing PCD and attenuates severe malaria

DK Raj, AD Mohapatra, A Jnawali, J Zuromski, A Jha… - Nature, 2020 - ncbi.nlm.nih.gov
Malaria caused by Plasmodium falciparum remains the leading single-agent killer of
children 1, yet the promise of an effective vaccine remains unfulfilled. Using our differential …

Malaria vaccines targeting the pre-erythrocytic stage: a scoping review

T Ogeto, F Ndubi, M Murithi, R Kagia… - …, 2020 - f1000research.com
Malaria is a deadly infectious parasitic disease that causes devastating morbidity and
mortality globally. Despite being a public health concern, an effective vaccine for prevention …

Commentary in reply to a publication on Plasmodium falciparum pre-erythrocytic stage vaccine development

FP Roman, M Coccia, L Schuerman - Malaria Journal, 2020 - Springer
We have read the publication of Molina-Franky and colleagues on Plasmodium falciparum
pre-erythrocytic stage vaccine development (Malaria Journal, 2020; 19: 56). The …

Day 7 concentration effects of partner drugs of artemisinin and derivatives on recurrent episodes of uncomplicated Plasmodium falciparum malaria after repetitive …

MM TEKETE - 2020 - archiv.ub.uni-heidelberg.de
The recommendation of artemisinin-based combination therapy (ACT) as a first line
treatment of malaria continues to be based only on data obtained from single episode …

[HTML][HTML] Development of Resistance Against Mefloquine Prophylaxis in Peace-Keeping Forces in the Central African Republic

JA Malik, A Nadeem, Z Khalid, Y Nadeem, S Zaffar… - Cureus, 2020 - ncbi.nlm.nih.gov
Development of Resistance Against Mefloquine Prophylaxis in Peace-Keeping Forces in the
Central African Republic - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Methods for Studying Memory B-Cell Immunity Against Malaria

P Jahnmatz - 2020 - search.proquest.com
Malaria är en sjukdom som orsakas av parasiter från släktet Plasmodium och vållar över
420.000 dödsfall årligen. Malaria är ett globalt problem, men koncentrerat främst till …

In-depth immunological analysis of prototypic adjuvants for vaccine formulations

L Roßmann - 2020 - openscience.ub.uni-mainz.de
Vaccine adjuvants have the potential to initiate, amplify and shape the immune response
against the vaccine antigen depending on their inherent mode of action (MoA). Thus, the …

Oxidative stree management is essential for anopheles mosquito survival post plasmodium infected blood meal ingestion

BB Tarimo - 2020 - dspace.nm-aist.ac.tz
Anopheles mosquitoes like other dipterans lack the flavoenzyme glutathione reductase (GR)
of the GSH pathway and instead utilize the Thioredoxin (Trx) system for management of …