The chromatin-remodelling complex SWI/SNF is highly conserved and has critical roles in various cellular processes, including transcription and DNA-damage repair,. It hydrolyses …
The generation of a local chromatin topology conducive to transcription is a key step in gene regulation 1. The yeast SWI/SNF complex is the founding member of a family of ATP …
G Da, J Lenkart, K Zhao… - Proceedings of the …, 2006 - National Acad Sciences
The SWIRM domain is a module found in the Swi3 and Rsc8 subunits of SWI/SNF-family chromatin remodeling complexes, and the Ada2 and BHC110/LSD1 subunits of chromatin …
L Tang, E Nogales, C Ciferri - Progress in biophysics and molecular …, 2010 - Elsevier
ATP-dependent chromatin remodeling complexes are specialized protein machinery able to restructure the nucleosome to make its DNA accessible during transcription, replication and …
SWI/SNF chromatin-remodeling complexes have crucial roles in transcription and other chromatin-related processes. The analysis of the two members of this class in …
ML Dechassa, B Zhang… - … and cellular biology, 2008 - Am Soc Microbiol
The SWI/SNF complex disrupts and mobilizes chromatin in an ATP-dependent manner. SWI/SNF interactions with nucleosomes were mapped by DNA footprinting and site-directed …
Protein complexes of the SWI/SNF family remodel nucleosome structure in an ATP- dependent manner. Each complex contains between 8 and 15 subunits, several of which …
CHROMATIN structure can affect the transcriptional activity of eukaryotic structural genes by blocking access of sequence-specific activator proteins (activators) to their promoter-binding …
J Côté, CL Peterson… - Proceedings of the …, 1998 - National Acad Sciences
To investigate the mechanism of SWI/SNF action, we have analyzed the pathway by which SWI/SNF stimulates formation of transcription factor-bound nucleosome core complexes. We …