Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome

FR Wagner, C Dienemann, H Wang, A Stützer… - Nature, 2020 - nature.com
Chromatin-remodelling complexes of the SWI/SNF family function in the formation of
nucleosome-depleted, transcriptionally active promoter regions (NDRs),. In the yeast …

Cryo-EM structure of SWI/SNF complex bound to a nucleosome

Y Han, AA Reyes, S Malik, Y He - Nature, 2020 - nature.com
The chromatin-remodelling complex SWI/SNF is highly conserved and has critical roles in
various cellular processes, including transcription and DNA-damage repair,. It hydrolyses …

Nucleosome mobilization catalysed by the yeast SWI/SNF complex

I Whitehouse, A Flaus, BR Cairns, MF White… - Nature, 1999 - nature.com
The generation of a local chromatin topology conducive to transcription is a key step in gene
regulation 1. The yeast SWI/SNF complex is the founding member of a family of ATP …

Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes

G Da, J Lenkart, K Zhao… - Proceedings of the …, 2006 - National Acad Sciences
The SWIRM domain is a module found in the Swi3 and Rsc8 subunits of SWI/SNF-family
chromatin remodeling complexes, and the Ada2 and BHC110/LSD1 subunits of chromatin …

Structure and function of SWI/SNF chromatin remodeling complexes and mechanistic implications for transcription

L Tang, E Nogales, C Ciferri - Progress in biophysics and molecular …, 2010 - Elsevier
ATP-dependent chromatin remodeling complexes are specialized protein machinery able to
restructure the nucleosome to make its DNA accessible during transcription, replication and …

Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast

BJ Monahan, J Villén, S Marguerat, J Bähler… - Nature structural & …, 2008 - nature.com
SWI/SNF chromatin-remodeling complexes have crucial roles in transcription and other
chromatin-related processes. The analysis of the two members of this class in …

Architecture of the SWI/SNF-nucleosome complex

ML Dechassa, B Zhang… - … and cellular biology, 2008 - Am Soc Microbiol
The SWI/SNF complex disrupts and mobilizes chromatin in an ATP-dependent manner.
SWI/SNF interactions with nucleosomes were mapped by DNA footprinting and site-directed …

Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits

ML Phelan, S Sif, GJ Narlikar, RE Kingston - Molecular cell, 1999 - cell.com
Protein complexes of the SWI/SNF family remodel nucleosome structure in an ATP-
dependent manner. Each complex contains between 8 and 15 subunits, several of which …

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

H Kwon, AN Imbalzano, PA Khavari, RE Kingston… - Nature, 1994 - nature.com
CHROMATIN structure can affect the transcriptional activity of eukaryotic structural genes by
blocking access of sequence-specific activator proteins (activators) to their promoter-binding …

Perturbation of nucleosome core structure by the SWI/SNF complex persists after its detachment, enhancing subsequent transcription factor binding

J Côté, CL Peterson… - Proceedings of the …, 1998 - National Acad Sciences
To investigate the mechanism of SWI/SNF action, we have analyzed the pathway by which
SWI/SNF stimulates formation of transcription factor-bound nucleosome core complexes. We …