Purpose The topically administered drugs through conventional delivery systems have low
bioavailability. Henceforth, the present study was designed to prepare and optimize …

In this study, chitosan nanoparticles (CH-NPs) were used to encapsulate antibacterial agent
levofloxacin for the treatment of ocular infection. The chitosan nanoparticles were prepared …

Methods: Formulation was optimized by 3-factors (CS, DS, and Mox concentration), 3-levels
(− 1, 0,+ 1) Box-Behnken design. Optimized formulation was characterized for various in …

Purpose The present study was designed to study the gentamycin (GTM)-loaded stimulus-
responsive chitosan nanoparticles to treat bacterial conjunctivitis. Methods GTM-loaded …

Lomefloxacin HCl (LF) is a widely used fourth-generation fluoroquinolone antibiotic. Like
most drug solutions administered via ocular route, it is usually eliminated by eye protective …

Eye inflammation is considered one of the most common co-morbidities associated with
ocular disorders and surgeries. Conventional management of this condition with non …

Purpose: A major challenge in ocular therapeutics is poor bioavailability of drug, 1% or even
less of the instilled dose is absorbed and frequent administration of conventional products …

In the present study, we aimed to formulate, optimize, and characterize azithromycin
chitosan coated niosomes (AZM-CTS-NSM) as a novel colloidal system that increases …

The present work aimed to develop nanoparticles of tobramycin (TRM) using thiolated
chitosan (TCS) in order to improve the mucoadhesion, antibacterial effect and …

This study was conducted to develop timolol maleate (TM)-loaded galactosylated chitosan
(GC) nanoparticles (NPs)(TM-GC-NPs) followed by optimization via a four-level and three …