ME Whalen, R Kajubi, J Goodwin… - Clinical Infectious …, 2023 - academic.oup.com
Background Artemether-lumefantrine (AL) is the most widely used artemisinin-based combination therapy in Sub-Saharan Africa and is threatened by the emergence of …
I Sagara, B Fofana, J Gaudart, B Sidibe… - The American journal …, 2012 - ncbi.nlm.nih.gov
Artemisinin-based combination therapies (ACTs) are the first-line treatment of uncomplicated malaria. The public health benefit and safety of repeated administration of a …
Background Achieving adequate antimalarial drug exposure is essential for curing malaria. Day 7 blood or plasma lumefantrine concentrations provide a simple measure of drug …
Background Combination treatments, preferably containing an artemisinin derivative, are recommended to improve efficacy and prevent Plasmodium falciparum drug resistance …
Abstract Background Parasitaemia on Day 3 has been proposed as a useful alert of potential artemisinin resistance, however, the normal variation of parasite clearance …
JLA Ndiaye, B Faye, A Gueye, R Tine, D Ndiaye… - Malaria journal, 2011 - Springer
Background The use of artemisinin-based combination therapy (ACT) is currently recommended for treating uncomplicated malaria. The objective was to assess the efficacy …
MT Bretscher, JT Griffin, P Hugo, M Baker, A Ghani… - Malaria journal, 2014 - Springer
Background Five artemisinin combination therapies (ACTs) are currently recommended for treatment of uncomplicated malaria in Africa. Whilst the artemisinin component has a short …
Artemisinin resistance is rapidly spreading in Southeast Asia. The efficacy of artemisinin- combination therapy (ACT) continues to be excellent across Africa. We performed parasite …
J Zwang, G Dorsey, A Mårtensson, U d'Alessandro… - Malaria Journal, 2014 - Springer
Background Artemisinin-based combination therapy (ACT) is the recommended first-line therapy for uncomplicated Plasmodium falciparum malaria worldwide but decreased …