A novel polymer of poloxamer188-b-PCL was synthesized via a ring-opening
polymerization. Fourier transform infrared spectroscopy (FTIR), Raman, and 1H nuclear …

Curcumin (CUR) is a food additive approved by World Health Organization. But the
shortcomings, such as poor water solubility, easy oxidation and degradation, limit its …

Curcumin, the principal polyphenolic curcuminoid, has been reported in numerous studies
for its antitumor effect in a series of cancers. It is also reported that curcumin possesses …

In this research, curcumin (CUR) conjugated albumin based nanoparticles (BSA-CUR) were
designed for improvement and evaluation radioprotective effect of CUR. In this way, we have …

When a burst of reactive oxygen species (ROS) is induced after radiation exposure, a
sufficient radioprotector drug must be quickly released to neutralize the ROS. An oral …

Protecting the body from radiation damage is a huge medical challenge. Amifostine and
curcumin are both effective radioprotectants, but their use has been greatly restricted due to …

Purpose: While the radioprotective activity of curcumin against genotoxicity has been well
established, its poor oral bioavailability has limited its successful clinical applications …

Doxorubicin (DOX) is widely used in the treatment of many tumors, but the dose-dependent
toxicity limits its further application. In this study, a unique strategy was developed to improve …

The aim of this work was to investigate the effect of triblock copolymer poloxamer 188 on
nanoparticle morphology, size, cancer cell uptake, and cytotoxicity. Docetaxel-loaded …

Curcumin (CUR) has been studied for its biomedical applications due to its active biological
properties. However, CUR has limitations such as poor solubility, low bioavailability, and …