Malaria caused by Plasmodium falciparum remains the leading single-agent killer of
children 1, yet the promise of an effective vaccine remains unfulfilled. Using our differential …

Malaria caused by Plasmodium falciparum remains the leading single-agent cause of
mortality in children, yet the promise of an effective vaccine has not been fulfilled. Here …

Background: Malaria affects almost one-half of the world's population and causes more than
600,000 deaths annually. Young children in malaria endemic areas of Africa have the …

Developing a vaccine to prevent malaria caused by the parasite Plasmodium falciparum has
proved highly challenging. Raj et al. now show that P. falciparum glutamic acid-rich protein …

Apoptosis is conventionally regarded as an evolutionarily conserved and genetically
controlled process of programmed cell death confined to metazoan organisms. However …

Results: Published text:“Four of the five monoclonal antibodies (CIS23, CIS34, CIS42 and
CIS43) showed dose-dependent binding to rPfCSP and PfSPZ in an ELISA and had …

Novel vaccines are urgently needed to reduce the burden of severe malaria. Using a
differential whole-proteome screening method, we identified Plasmodium falciparum …

The feasibility of a malaria vaccine is supported by the fact that children in endemic areas
develop naturally acquired immunity to disease. Development of disease immunity is …

Plasmodium falciparum glutamic acid-rich protein (PfGARP) is a recently characterized cell
surface antigen encoded by Plasmodium falciparum, the causative agent of severe human …

Naturally acquired anti-Plasmodium falciparum immunity protects first and foremost against
severe disease. Raj et al. have established a tantalizing path towards an anti-disease …