Vaccine adjuvants have the potential to initiate, amplify and shape the immune response
against the vaccine antigen depending on their inherent mode of action (MoA). Thus, the …

Adjuvants are critical components of vaccines that enhance the host immune response to
the vaccine antigen, however, only a small number of adjuvants are used in vaccines …

Adjuvants have long been critical components of vaccines, but the exact mechanisms of
their action and precisely how they alter or enhance vaccine-induced immune responses …

After decades of slow progress, the last years have seen a rapid acceleration of the
development of adjuvanted vaccines which have lately been approved for human use …

Background The need for rapid and accurate comparison of panels of adjuvanted vaccine
formulations and subsequent rational down selection, presents several challenges for …

The assessment of modern sub-unit vaccines reveals that the generation of neutralizing
antibodies is important but not sufficient for adjuvant selection. Therefore, adjuvants with …

Adjuvants produce complex, but often subtle, effects on vaccine-induced immune responses
that, nonetheless, play a critical role in vaccine efficacy. In-depth profiling of vaccine-induced …

Since the first mass vaccination against smallpox and its eventual eradication, many more
vaccines have been developed based on advances in bacteriology and virology and the use …

Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …

Vaccination represents one of the greatest public health triumphs; in part due to the effect of
adjuvants that have been included in vaccine preparations to boost the immune responses …