I would like to thank God for being with me throughout this journey. Indeed, I saw the work of
His hands as He moved things and repositioned them in my favor. I cannot thank my parents …

The keystone for the treatment of malaria is artemisininbased combination therapy (ACT).
The vulnerability of parasites to ACT has, regrettably, declined. Determining new …

Aims: To determine the toxicity of astemizole-methylene blue combination therapy as
effective candidates for therapeutic repurposing against malaria. Study Design: Randomized …

The present work deals with the development of Plasmodium falciparum stages in mouse
model and its potential for the study of efficacy of antimalarial drugs. C57BL/6J mice were …

To find out the efficacy and effect of artemisinin derivatives on haematological indices,
C57BL/6J mice were challenged with Plasmodium falciparum and treated with therapeutic …

Background: Malaria is common in regions like sub-Saharan Africa and South East Asia,
where it results in millions of mortalities per year. Resistance to currently available …

The antimalarial activity of combinations of mefloquine or artesunic acid with ciprofloxacin
and other synthetic fluoroquinolone was tested in vitro against Plasmodium falciparum using …

Methilene blue was reported as the first synthetic antimalarial by Ehrlich in 1881. It is
currently no longer used for that purpose but it should be reconsidered since new economic …

Abstract Background Intravenous artesunate (IV AS) is the present treatment of choice for
severe malaria, but development of artemisinin resistance indicates that a further agent will …

Aims: To determine the toxicity of astemizole-methylene blue combination therapy as
effective candidates for therapeutic repurposing against malaria. Study Design: Randomized …