Research has focused more and more on the interplay between genetics and environment
in predicting different forms of psychopathology, including depressive symptoms. While the …

Early-life adversity caused by poor social bonding and deprived maternal care is known to
affect mental wellbeing and physical health. It is a form of chronic social stress that persists …

Background An early onset of depression is associated with higher chronicity and disability,
more stressful life events (SLEs), higher negative emotionality as described by the primary …

Childhood abuse (CA) is a prevalent global health concern, increasing the risk of negative
mental health outcomes later in life. In the literature, CA is commonly defined as physical …

Our aims were to evaluate the depression model of early maternal separation (MS)
combined with adolescent chronic unpredictable mild stress (CUMS) in female adult SD rats …

Acute kidney injury (AKI) is a widely held concern related to a substantial burden of
morbidity, mortality and expenditure in the healthcare system. AKI is not a simple illness but …

Background Several psychological studies have shown that depressive rumination is
associated with the onset and severity of depression. However, it is unclear how rumination …

Background Kratom is a psychoactive plant preparation originating from Southeast Asia. It
has been used as a recreational and performance drug in Southeast Asia, and is now …

Alcohol use disorder (AUD) is a very common and complex disease, as alcohol is the most
widely used addictive drug in the world. This disorder has an enormous impact on public …

Depression is a prevalent neuropsychiatric disease with a high recurrence rate, affecting
over 350 million people worldwide. Intestinal flora disorders and gut-brain-axis (GBA) …