Management of familial hypercholesterolemia: current status and future perspectives

DTW Lui, ACH Lee, KCB Tan - Journal of the Endocrine Society, 2021 - academic.oup.com
Familial hypercholesterolemia (FH) is the most common monogenic disorder associated
with premature atherosclerotic cardiovascular disease. Early diagnosis and effective …

Association of multiple metals with lipid markers against different exposure profiles: A population-based cross-sectional study in China

Z Li, Y Xu, Z Huang, Y Wei, J Hou, T Long, F Wang… - Chemosphere, 2021 - Elsevier
We sought to evaluate whether essential and toxic metals are cross-sectionally related to
blood lipid levels using data among adults from Shimen (n= 564) and Huayuan (n= 637) …

Cost-effectiveness of lipid-lowering treatments in young adults

CN Kohli-Lynch, BK Bellows, Y Zhang, B Spring… - Journal of the American …, 2021 - jacc.org
Background Raised low-density lipoprotein cholesterol (LDL-C) in young adulthood (aged
18-39 years) is associated with atherosclerotic cardiovascular disease (ASCVD) later in life …

Association of non–high-density lipoprotein cholesterol measured in adolescence, young adulthood, and mid-adulthood with coronary artery calcification measured in …

MK Armstrong, BJ Fraser, O Hartiala, MJ Buscot… - JAMA …, 2021 - jamanetwork.com
Importance Elevated non–high-density lipoprotein cholesterol (non–HDL-C) is associated
with the presence of coronary artery calcification (CAC), a marker of heart disease in …

Intensity of statin therapy and muscle symptoms: a network meta-analysis of 153 000 patients

JW Davis, SC Weller - BMJ open, 2021 - bmjopen.bmj.com
Objective To estimate relative risk (RR) of statin-associated musculoskeletal symptoms by
statin therapy intensity. Setting Network meta-analysis assessing multicentre randomised …

Cardiovascular disease risk–based statin utilization and associated outcomes in a primary prevention cohort: insights from a large health care network

A Saeed, J Zhu, F Thoma, O Marroquin… - … Quality and Outcomes, 2021 - Am Heart Assoc
Background: Current American College of Cardiology/American Heart Association
guidelines recommend using the 10-year atherosclerotic cardiovascular disease (ASCVD) …

[HTML][HTML] Nutrition, atherosclerosis, arterial imaging, cardiovascular risk stratification, and manifestations in COVID-19 framework: A narrative review

S Munjral, P Ahluwalia, AD Jamthikar… - Frontiers in bioscience …, 2021 - imrpress.com
Background: Atherosclerosis is the primary cause of the cardiovascular disease (CVD).
Several risk factors lead to atherosclerosis, and altered nutrition is one among those …

Cost-effectiveness of coronary artery calcium scoring in people with a family history of coronary disease

P Venkataraman, H Kawakami, Q Huynh… - Cardiovascular …, 2021 - jacc.org
Objectives To assess the cost effectiveness of coronary artery calcium (CAC) compared with
traditional risk factor–based prediction alone in those with an family history of premature …

[HTML][HTML] Linderae radix ethanol extract alleviates diet-induced hyperlipidemia by regulating bile acid metabolism through gut microbiota

T Jiang, C Xu, H Liu, M Liu, M Wang, J Jiang… - Frontiers in …, 2021 - frontiersin.org
Hyperlipidemia is a common metabolic disorder and regarded as one of the main risk factors
for cardiovascular disease. The gut microbiota has been identified as a potential contributor …

[HTML][HTML] The relationship between cardiovascular risk scores and several markers of subclinical atherosclerosis in an asymptomatic population

O Mitu, A Crisan, S Redwood… - Journal of clinical …, 2021 - mdpi.com
Background: The current cardiovascular disease (CVD) primary prevention guidelines
prioritize risk stratification by using clinical risk scores. However, subclinical atherosclerosis …