Background Obesity, characterized by an increased amount of adipose tissue, is a metabolic
chronic alteration which has reached pandemic proportion. Lifestyle changes are the first …

MicroRNAs (miRNAs), a class of small, non-coding RNA molecules, play an important role in
the posttranscriptional regulation of gene expression, thereby influencing important cellular …

Abstract The 3T3-L1 murine pre-adipocyte line is an established cell culture model for
screening Metabolism Disrupting Chemicals (MDCs). Despite a need to accurately identify …

Lipids and carbohydrates regulate gene expression by means of molecules that sense these
macronutrients and act as transcription factors. The peroxisome proliferator-activated …

Abstract The effects of Endocrine Disrupting Chemicals (EDCs) on the current obesity
epidemic is a growing field of interest. Numerous EDCs have shown the potential to alter …

Age-related bone loss is inevitable in both men and women and there will soon be more
people of extreme old age than ever before. Osteoporosis is a common chronic disease and …

Introduction: Obesity and related metabolic disturbances are frequently related to modern
lifestyle and are characterized by excessive fructose intake. Visceral adipose tissue (VAT) …

Mesenchymal stem cells (MSC) are multipotent cells capable to differentiate into adipogenic,
osteogenic, and chondrogenic directions, possessing immunomodulatory activity and a …

The literature has reported a higher prevalence of negative clinical outcomes due to
Coronavirus disease 19 (COVID-19) in obese individuals. This can be explained by the …

Ethnopharmacological relevance Phyto-preparations and phyto-compounds, by their natural
origin, easy availability, cost-effectiveness, and fruitful traditional uses based on …