Endogenous feline leukemia virus (FeLV) siRNA transcription may interfere with exogenous FeLV infection

ES Chiu, CA McDonald, S VandeWoude - Journal of Virology, 2021 - Am Soc Microbiol
Endogenous retroviruses (ERVs) are increasingly recognized for biological impacts on host
cell function and susceptibility to infectious agents, particularly in relation to interactions with …

Oligonucleotide-based approaches to inhibit dengue virus replication

K Panda, K Alagarasu, D Parashar - Molecules, 2021 - mdpi.com
Dengue fever is one of the most common viral infections affecting humans. It is an
expanding public health problem, particularly in tropical and subtropical regions. No …

Modeling neoplastic growth in renal cell carcinoma and polycystic kidney disease

C Millet-Boureima, S He, TBU Le… - International Journal of …, 2021 - mdpi.com
Renal cell carcinoma (RCC) and autosomal dominant polycystic kidney disease (ADPKD)
share several characteristics, including neoplastic cell growth, kidney cysts, and limited …

Non-cationic RGD-containing protein nanocarrier for tumor-targeted siRNA delivery

X Yu, L Xue, J Zhao, S Zhao, D Wu, HY Liu - Pharmaceutics, 2021 - mdpi.com
Despite the recent successes in siRNA therapeutics, targeted delivery beyond the liver
remains the major hurdle for the widespread application of siRNA in vivo. Current cationic …

Quaternized starch-based composite nanoparticles for siRNA delivery to tumors

E Amar-Lewis, N Buaron, R Chintakunta… - ACS Applied Nano …, 2021 - ACS Publications
RNA interference (RNAi) therapy has emerged as a promising cancer therapy platform;
however, there is an ongoing need for a safe and effective delivery carrier for siRNA. The …

mirMachine: a one-stop shop for plant miRNA annotation

HB Cagirici, TZ Sen, H Budak - JoVE (Journal of Visualized Experiments), 2021 - jove.com
Of different types of noncoding RNAs, microRNAs (miRNAs) have arguably been in the
spotlight over the last decade. As post-transcriptional regulators of gene expression …

The application of antisense technology for crop improvement: A review

T Tilahun, Y Bezie, B Kerisew, M Taye - Cogent Food & Agriculture, 2021 - Taylor & Francis
The global population is increasing alarmingly, which calls for efficient methods of food
production. Since domestication, people have been working on improving food crops for …

Iron oxide-based polymeric magnetic nanoparticles for drug and gene delivery: in vitro and in vivo applications in cancer

S Yalcin, U Gündüz - Handbook of polymer and ceramic nanotechnology, 2021 - Springer
In the war against cancer, nanotechnology has important role by improving the efficacy of
traditional therapies. Nanoparticle-based drug delivery system has many advantages …

Improving antibody production in stably transfected CHO cells by CRISPR‐Cas9‐mediated inactivation of genes identified in a large‐scale screen with Chinese …

PC Lin, R Liu, K Alvin, S Wahyu, N Murgolo… - Biotechnology …, 2021 - Wiley Online Library
The Chinese hamster ovary (CHO) cell line is commonly used for the production of
biotherapeutics. As cell productivity directly affects the cost of production, methods are …

Decaffeinated coffee and green tea extract inhibit foam cell atherosclerosis by lowering inflammation and improving cholesterol influx/efflux balance through …

E Rachmawati, MS Rohman, D Sargowo… - …, 2021 - repository.uin-malang.ac.id
Background: Foam cell is the marker of initial phase of atherosclerosis and determine the
development of advance atherosclerotic plaque which is stimulated by the presence of …